5-broMo-N,N,6-triMethylpyridin-2-aMine

Base Information

• Chemical Name: 5-broMo-N,N,6-triMethylpyridin-2-aMine
• CAS No.: 910054-73-8
• Molecular Formula: C₈H₁₁BrN₂
• Molecular Weight: 215.093
• Hs Code.: 2933399090
• Mol file: 910054-73-8.mol

Synonyms:5-broMo-N,N,6-triMethylpyridin-2-aMine;(5-Bromo-6-methyl-pyridin-2-yl)-dimethyl-amine

Chemical Property of 5-broMo-N,N,6-triMethylpyridin-2-aMine

Chemical Property:

• PSA: 16.13000
• LogP: 2.21850
• Storage Temp.: 2-8°C

Purity/Quality:

95+% ^*data from raw suppliers

5-Bromo-N,N,6-trimethylpyridin-2-amine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-broMo-N,N,6-triMethylpyridin-2-aMine

There total 2 articles about 5-broMo-N,N,6-triMethylpyridin-2-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

5-bromo-6-methyl-pyridin-2-ylamine (42753-71-9) + methyl iodide (74-88-4) → (5-bromo-6-methyl-pyridin-2-yl)-dimethyl-amine (910054-73-8)

Guidance literature:

5-bromo-6-methyl-pyridin-2-ylamine; With sodium hydride; In tetrahydrofuran; for 0.5h;

methyl iodide; In tetrahydrofuran; for 24h;

With sodium hydride; In tetrahydrofuran; for 72h;

Reference yield:

5-bromo-6-methyl-pyridin-2-ylamine (42753-71-9) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → (5-bromo-6-methyl-pyridin-2-yl)-dimethyl-amine (910054-73-8)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In acetonitrile; at 20 ℃;

DOI:10.1021/jm040058e

Reference yield:

N,N-dimethyl-formamide (68-12-2,33513-42-7) + (5-bromo-6-methyl-pyridin-2-yl)-dimethyl-amine (910054-73-8) → 6-dimethylamino-2-methyl-pyridine-3-carbaldehyde (1027421-95-9)

Guidance literature:

(5-bromo-6-methyl-pyridin-2-yl)-dimethyl-amine; With magnesium; ethylene dibromide; In tetrahydrofuran;

N,N-dimethyl-formamide; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/jm040058e

upstream raw materials:

5-bromo-6-methyl-pyridin-2-ylamine

formaldehyd

methyl iodide

Downstream raw materials:

6-dimethylamino-2-methyl-pyridine-3-carbaldehyde