1-(4-Bromophenyl)ethyl methyl ether

Base Information

• Chemical Name: 1-(4-Bromophenyl)ethyl methyl ether
• CAS No.: 59891-97-3
• Molecular Formula: C9H11BrO
• Molecular Weight: 215.09
• Hs Code.: 2909309090
• European Community (EC) Number: 887-194-8
• Nikkaji Number: J1.085.769D
• Mol file: 59891-97-3.mol

Synonyms:1-(4-bromophenyl)ethyl methyl ether;1-bromo-4-(1-methoxyethyl)benzene;59891-97-3;1-bromo-4-[(1R)-1-methoxyethyl]benzene;1-bromo-4-[(1S)-1-methoxyethyl]benzene;SCHEMBL3322412;DUCFFBWPWJEFDI-UHFFFAOYSA-N;1-(4-Bromophenyl)ethylmethyl ether;MFCD12027065;STK503426;1-bromo-4-(1-methoxy-ethyl)-benzene;AKOS005171565;AM87950;BS-29114;CS-0207670;N11516;EN300-6776533

Chemical Property of 1-(4-Bromophenyl)ethyl methyl ether

Chemical Property:

• PSA: 9.23000
• LogP: 3.15650
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 213.99933
• Heavy Atom Count: 11
• Complexity: 108

Purity/Quality:

98%min ^*data from raw suppliers

1-(4-bromophenyl)ethylmethylether ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=C(C=C1)Br)OC

Technology Process of 1-(4-Bromophenyl)ethyl methyl ether

There total 6 articles about 1-(4-Bromophenyl)ethyl methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

triethylsilane (617-86-7) + 2-(4-Bromophenyl)-2,2-dimethoxyethane (53578-00-0) → (rac.)-1-bromo-4-(1-methoxyethyl)benzene (59891-97-3)

Guidance literature:

With 2,4,6-triphenylpyrilium perchlorate; In acetonitrile; for 0.5h; Irradiation;

DOI:10.1016/0040-4039(96)01776-5

Reference yield: 59.0%

2-(4-Bromophenyl)-2,2-dimethoxyethane (53578-00-0) → (rac.)-1-bromo-4-(1-methoxyethyl)benzene (59891-97-3)

Guidance literature:

With boron trifluoride diethyl etherate; sodium cyanoborohydride; In tetrahydrofuran; for 3.5h; Ambient temperature;

DOI:10.1016/0040-4020(95)00055-D

Reference yield: 46.0%

methanol (67-56-1) + 2-(4-bromophenyl)propionic acid (53086-53-6) → (rac.)-1-bromo-4-(1-methoxyethyl)benzene (59891-97-3)

Guidance literature:

With pyridine; copper(II) bis(trifluoromethanesulfonate); acetonitrile; In toluene; at 20 ℃; Irradiation; Inert atmosphere;

DOI:10.1038/s41557-021-00834-8

upstream raw materials:

methanol

1-bromo-4-(1-bromoethyl)benzene

2-(4-Bromophenyl)-2,2-dimethoxyethane

1-(4-bromophenyl)ethanol

Downstream raw materials:

(p-Diphenyl-phosphinophenyl)-1-methoxyaethan

1-(p-Dicyclohexyl-phosphinophenyl)-1-methoxyaethan

1-(p-Dicyclohexylphosphinylphenyl)-1-methoxyaethan

1-Chloro-1-(p-dicyclohexylphosphinylphenyl)aethan

Refernces

• 1、 -. "TRIAZOLE COMPOUNDS AS T-TYPE CALCIUM CHANNEL BLOCKERS". Page/Page column 48. . Retrieved 2016/04/09.
• 2、 Srikrishna,Viswajanani. "Tri-n-butylstannyl chloride-sodium cyanoborohydride mediated regioselective reductive demethoxylation of alkyl methyl ketals". . p. 621 - 625. Retrieved 2007/10/03.