3α-Ethoxycarbonyloxy-7α,12α-dihydroxy-5β-cholan-24-oic acid methyl ester

Base Information

• Chemical Name: 3α-Ethoxycarbonyloxy-7α,12α-dihydroxy-5β-cholan-24-oic acid methyl ester
• CAS No.: 21059-36-9
• Molecular Formula: C28H46O7
• Molecular Weight: 494.669
• Mol file: 21059-36-9.mol

Synonyms:3α-Ethoxycarbonyloxy-7α,12α-dihydroxy-5β-cholan-24-oic acid methyl ester

Chemical Property of 3α-Ethoxycarbonyloxy-7α,12α-dihydroxy-5β-cholan-24-oic acid methyl ester

Chemical Property:

• PSA: 102.29000
• LogP: 4.71790

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3α-Ethoxycarbonyloxy-7α,12α-dihydroxy-5β-cholan-24-oic acid methyl ester

There total 4 articles about 3α-Ethoxycarbonyloxy-7α,12α-dihydroxy-5β-cholan-24-oic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

chloroformic acid ethyl ester (541-41-3) + Cholsaeure-methylester (861-83-6,1448-36-8,14772-93-1,20231-70-3,28050-54-6,28050-56-8,71883-63-1,71883-65-3,81702-92-3,81702-93-4,81702-94-5,110715-93-0,110715-94-1,110715-95-2,110715-96-3,110715-97-4,110769-71-6) → 3α-Ethoxycarbonyloxy-7α,12α-dihydroxy-5β-cholansaeure-methylester (21059-36-9,83861-28-3)

Guidance literature:

With pyridine;

DOI:10.1002/ardp.19813140205

Reference yield:

→ 3-O-Aethoxycarbonyl-cholsaeuremethylester; 3-O-Cathyl-cholsaeuremethylester (21059-36-9,83861-28-3)

Guidance literature:

aus Cholsaeure-methylester und Chlorameisensaeure-aethylester;

DOI:10.1021/jo01271a041

Reference yield:

→ Methyl-3α-Carbethoxy-7α,12α-dihydroxy-5β-cholanat (21059-36-9,83861-28-3)

Guidance literature:

aus Trihydroxycholanat I m. C2H5-COOCl;

DOI:10.1021/bi00874a018

upstream raw materials:

chloroformic acid ethyl ester

Cholsaeure-methylester

deoxycholic acid

Downstream raw materials:

3α-ethoxycarbonyloxy-7,12-dioxo-5β-cholan-24-oic acid methyl ester

methyl 3α-ethoxycarbonyloxy-12α-hydroxy-7-oxo-5β-cholanate

methyl cholate

methyl 3α,12α-dihydroxy-7-oxo-5β-cholanate