2-(Aminomethyl)-2-(hydroxymethyl)propane-1,3-diol

Base Information

• Chemical Name: 2-(Aminomethyl)-2-(hydroxymethyl)propane-1,3-diol
• CAS No.: 7332-39-0
• Molecular Formula: C₅H₁₃NO₃
• Molecular Weight: 135.163
• DSSTox Substance ID: DTXSID601232652
• Mol file: 7332-39-0.mol

Synonyms:7332-39-0;2-(aminomethyl)-2-(hydroxymethyl)propane-1,3-diol;1,3-Propanediol, 2-(aminomethyl)-2-(hydroxymethyl)-;Tris(hydroxymethyl)aminoethane;SCHEMBL157477;2-(aminomethyl)-2-(hydroxymethyl)-1,3-Propanediol;QHQZEEGNGSZBOL-UHFFFAOYSA-N;DTXSID601232652;AKOS006339190;FT-0763643;EN300-6448454

Chemical Property of 2-(Aminomethyl)-2-(hydroxymethyl)propane-1,3-diol

Chemical Property:

• XLogP3: -2.7
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 135.08954328
• Heavy Atom Count: 9
• Complexity: 64.3

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(C(CO)(CO)CO)N

Technology Process of 2-(Aminomethyl)-2-(hydroxymethyl)propane-1,3-diol

There total 1 articles about 2-(Aminomethyl)-2-(hydroxymethyl)propane-1,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N'-bis(2,3-dihydroxypropyl)-5-{2-[(3-hydroxy-2,2-bis(hydroxymethyl)propyl)amino]-2-oxoethoxy}-1,3-benzenedicarboxamide → 2,2,2-tris(hydroxymethyl)ethylamine (7332-39-0) + [3,5-Bis-(2,3-dihydroxy-propylcarbamoyl)-phenoxy]-acetic acid

Guidance literature:

With water; at 95 ℃; Rate constant;

Reference yield: 95.0%

2,2,2-tris(hydroxymethyl)ethylamine (7332-39-0) + 5-chlorosalicyclaldehyde (635-93-8) → 2-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-ylimino)methyl)-4-chlorophenol

Guidance literature:

In ethanol; at 100 ℃; for 3h;

DOI:10.1016/j.poly.2016.02.042

Reference yield: 88.0%

2,2,2-tris(hydroxymethyl)ethylamine (7332-39-0) + salicylaldehyde (90-02-8) → 2-((2-hydroxy-benzylidene)-amino)-2-hydroxymethyl-propane-1,3-diol (18212-81-2)

Guidance literature:

In ethanol; at 100 ℃; for 3h;

DOI:10.1016/j.poly.2016.02.042

Downstream raw materials:

2-((2-hydroxy-benzylidene)-amino)-2-hydroxymethyl-propane-1,3-diol

2-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-ylimino)methyl)-4-bromophenol