tert-butyl 2-methyl-1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate

Base Information

Chemical Name:tert-butyl 2-methyl-1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate
CAS No.:923009-51-2
Molecular Formula:C₁₅H₂₆N₂O₃
Molecular Weight:282.383
Hs Code.:

Synonyms:2,7-Diazaspiro[4.5]decane-7-carboxylic acid, 2-ethyl-1-oxo-, 1,1-diMethylethyl ester

Suppliers and Price of tert-butyl 2-methyl-1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 2-methyl-1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate

Chemical Property:

Vapor Pressure:1.02E-06mmHg at 25°C
Boiling Point:403.5°C at 760 mmHg
Flash Point:197.8°C
PSA：49.85000
Density:1.13g/cm³
LogP:2.13170

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 2-methyl-1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate

There total 3 articles about tert-butyl 2-methyl-1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 923009-50-1
tert-butyl 1-oxo-2,7-diazaspiro[4,5]decane-7-carboxylate

: 75-03-6
ethyl iodide

: 923009-51-2
C₁₅H₂₆N₂O₃

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 60 ℃;
DOI:10.1016/j.bmcl.2011.08.117

Reference yield:

: 923009-49-8
1-(tert-butyl) 3-ethyl 3-(cyanomethyl)piperidine-1,3-dicarboxylate

: 923009-51-2
C₁₅H₂₆N₂O₃

Guidance literature:: Multi-step reaction with 2 steps

1: ammonia; hydrogen / methanol; water / 3750.38 Torr

2: sodium hydride / tetrahydrofuran / 60 °C

With ammonia; hydrogen; sodium hydride; In tetrahydrofuran; methanol; water;
DOI:10.1016/j.bmcl.2011.08.117

Reference yield:

: 148672-74-6,130250-54-3
ethyl N-(t-butyloxycarbonyl)nipecotate

: 923009-51-2
C₁₅H₂₆N₂O₃

Guidance literature:: Multi-step reaction with 3 steps

1: lithium hexamethyldisilazane / tetrahydrofuran / -78 °C

2: ammonia; hydrogen / methanol; water / 3750.38 Torr

3: sodium hydride / tetrahydrofuran / 60 °C

With ammonia; hydrogen; sodium hydride; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; water;
DOI:10.1016/j.bmcl.2011.08.117