4-BroMo-1-(iso-propyl)-1H-iMidazole

Base Information

• Chemical Name: 4-BroMo-1-(iso-propyl)-1H-iMidazole
• CAS No.: 623577-60-6
• Molecular Formula: C6H9BrN2
• Molecular Weight: 189.055
• Hs Code.: 29332900
• Mol file: 623577-60-6.mol

Synonyms:4-BroMo-1-(iso-propyl)-1H-iMidazole;4-Bromo-1-(prop-2-yl)-1H-imidazole;4-bromo-1-propan-2-ylimidazole

Chemical Property of 4-BroMo-1-(iso-propyl)-1H-iMidazole

Chemical Property:

• PSA: 17.82000
• LogP: 2.22650
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%, ^*data from raw suppliers

4-bromo-1-isopropyl-1H-imidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BroMo-1-(iso-propyl)-1H-iMidazole

There total 4 articles about 4-BroMo-1-(iso-propyl)-1H-iMidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

isopropyl bromide (75-26-3) → 4-bromo-1-(propan-2-yl)-1H-imidazole (623577-60-6)

Guidance literature:

4-bromo-1 H-imidazole; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.5h;

isopropyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 15h;

Reference yield: 15.55%

4-bromo-1 H-imidazole (2302-25-2) + isopropyl bromide (75-26-3) → 4-bromo-1-(propan-2-yl)-1H-imidazole (623577-60-6)

Guidance literature:

4-bromo-1 H-imidazole; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

isopropyl bromide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 16h;

Reference yield:

2-iodo-propane (75-30-9) + 4-bromo-1 H-imidazole (2302-25-2) → 4-bromo-1-(propan-2-yl)-1H-imidazole (623577-60-6)

Guidance literature:

With caesium carbonate; In acetone; at 55 ℃; for 15h;

upstream raw materials:

isopropyl bromide

4-bromo-1 H-imidazole

2-iodo-propane

1-isopropyllimidazole

Refernces

• 1、 -. "SUBSTITUTED PYRAZOLOPYRIMIDINES AND SUBSTITUTED PURINES AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS". Paragraph 0582. . Retrieved 2020/07/14.
• 2、 -. "HETEROARYL SUBSTITUTED SPIROCYCLIC SULFAMIDES FOR INHIBITION OF GAMMA SECRETASE". Page/Page column 117. . Retrieved 2008/06/13.