4-Chlorothiobenzoic acid S-ethyl ester

Base Information

• Chemical Name: 4-Chlorothiobenzoic acid S-ethyl ester
• CAS No.: 28145-62-2
• Molecular Formula: C9H9ClOS
• Molecular Weight: 200.689
• Hs Code.: 2930909090
• Mol file: 28145-62-2.mol

Synonyms:4-Chlorobenzenethiocarboxylic acid S-ethyl ester;4-Chlorothiobenzoic acid S-ethyl ester;p-Chlorobenzenethiocarboxylic acid S-ethyl ester

Chemical Property of 4-Chlorothiobenzoic acid S-ethyl ester

Chemical Property:

• PSA: 42.37000
• LogP: 3.23330

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Chlorothiobenzoic acid S-ethyl ester

There total 2 articles about 4-Chlorothiobenzoic acid S-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-chloro-benzoyl chloride (122-01-0) + ethanethiol (75-08-1) → S-ethyl 4-chlorobenzenecarbothioate (28145-62-2)

Guidance literature:

With zinc; In toluene; for 5h; Ambient temperature;

DOI:10.1055/s-1998-1797

Reference yield:

ethanethiol (75-08-1) + para-chlorobenzoic acid (74-11-3) → S-ethyl 4-chlorobenzenecarbothioate (28145-62-2)

Guidance literature:

With sulfuryl dichloride; Multistep reaction;

DOI:10.1039/c39940002081

Reference yield: 90.0%

S-ethyl 4-chlorobenzenecarbothioate (28145-62-2) → 4-Chlorthiobenzoesaeure-ethylthioester (27249-72-5)

Guidance literature:

With Lawessons reagent; In toluene; Inert atmosphere; Reflux;

DOI:10.1016/j.tet.2010.03.045

upstream raw materials:

4-chloro-benzoyl chloride

ethanethiol

para-chlorobenzoic acid

Downstream raw materials:

1-Chloro-4-(1-ethylsulfanyl-2-methyl-propenyl)-benzene

4-Chlorthiobenzoesaeure-ethylthioester

ethanethiol

para-chlorobenzoic acid