Alpha-Bromo-cyclopentanepropanoic acidmethylester

Base Information

• Chemical Name: Alpha-Bromo-cyclopentanepropanoic acidmethylester
• CAS No.: 1191453-82-3
• Molecular Formula: C9H15BrO2
• Molecular Weight: 235.121
• Hs Code.: 2916209090
• Mol file: 1191453-82-3.mol

Synonyms:Alpha-Bromo-cyclopentanepropanoic acidmethylester;Cyclopentanepropanoic acid, a-broMo-, Methyl ester;Methyl 2-broMo-3-cyclopentylpropionate;methyl 2-bromo-3-cyclopentylpropanoate;2-bromo-3-cyclopentyl-propionic acid methyl ester

Chemical Property of Alpha-Bromo-cyclopentanepropanoic acidmethylester

Chemical Property:

• PSA: 26.30000
• LogP: 2.50320

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-bromo-3-cyclopentylpropionate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Alpha-Bromo-cyclopentanepropanoic acidmethylester

There total 3 articles about Alpha-Bromo-cyclopentanepropanoic acidmethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 2-bromo-3-cyclopentyl-propionyl chloride (1191455-56-7) → 2-bromo-3-cyclopentyl-propionic acid methyl ester (1191453-82-3)

Guidance literature:

In tetrachloromethane; water; at 0 ℃;

Reference yield:

3-cyclopentylpropionic acid (140-77-2) → 2-bromo-3-cyclopentyl-propionic acid methyl ester (1191453-82-3)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / tetrachloromethane / 0.5 h / 65 °C

2: N-Bromosuccinimide / hydrogen bromide / tetrachloromethane; water / 3.17 h / 70 - 85 °C

3: tetrachloromethane / 0 °C

With N-Bromosuccinimide; thionyl chloride; hydrogen bromide; In tetrachloromethane; water;

Reference yield:

cyclopentanepropanoyl chloride (104-97-2) → 2-bromo-3-cyclopentyl-propionic acid methyl ester (1191453-82-3)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide / hydrogen bromide / tetrachloromethane; water / 3.17 h / 70 - 85 °C

2: tetrachloromethane / 0 °C

With N-Bromosuccinimide; hydrogen bromide; In tetrachloromethane; water;

upstream raw materials:

methanol

2-bromo-3-cyclopentyl-propionyl chloride

3-cyclopentylpropionic acid

cyclopentanepropanoyl chloride

Downstream raw materials:

3-cyclopentyl-2-(4,5-dichloro-6-oxo-6H-pyridazin-1-yl)-propionic acid methyl ester

3-cyclopentyl-2-(6-oxo-4-phenoxy-6H-pyridazin-1-yl)-propionic acid methyl ester

2-[4-(2-acetyl-phenoxy)-6-oxo-6H-pyridazin-1-yl]-3-cyclopentyl-propionic acid methyl ester

2-[4-(2-cyano-phenoxy)-6-oxo-6H-pyridazin-1-yl]-3-cyclopentyl-propionic acid methyl ester