2-[4-(Pyridin-2-yl)piperazin-1-yl]ethan-1-ol

Base Information

Chemical Name:2-[4-(Pyridin-2-yl)piperazin-1-yl]ethan-1-ol
CAS No.:40004-68-0
Molecular Formula:C₁₁H₁₇N₃O
Molecular Weight:207.275
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90441049
Wikidata:Q82257606
Mol file:40004-68-0.mol

Synonyms:40004-68-0;2-(4-pyridin-2-ylpiperazin-1-yl)ethanol;4-(2-Pyridinyl)-1-piperazineethanol;2-[4-(Pyridin-2-yl)piperazin-1-yl]ethan-1-ol;2-(4-(Pyridin-2-yl)piperazin-1-yl)ethan-1-ol;4-(PYRIDIN-2-YL)-1-PIPERAZINEETHANOL;SCHEMBL2522222;DTXSID90441049;JADLXZSDPDFNLC-UHFFFAOYSA-N;4-(2-pyridyl)-1-piperazineethanol;AKOS008923540;CS-0355462;Z31248553;1-METHYL-2-MORPHOLIN-4-YL-2-PHENYLETHYLAMINEHYDROCHLORIDE

Suppliers and Price of 2-[4-(Pyridin-2-yl)piperazin-1-yl]ethan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
1-[3-(1-Pyrrolidinylcarbonyl)-2-pyridinyl]piperazine AldrichCPR
1g
$ 68.30

Total 1 raw suppliers

Chemical Property of 2-[4-(Pyridin-2-yl)piperazin-1-yl]ethan-1-ol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:377.766°C at 760 mmHg
Flash Point:182.266°C
PSA：39.60000
Density:1.145g/cm³
LogP:0.19880
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:207.137162174
Heavy Atom Count:15
Complexity:181

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-[3-(1-Pyrrolidinylcarbonyl)-2-pyridinyl]piperazine AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCO)C2=CC=CC=N2

Technology Process of 2-[4-(Pyridin-2-yl)piperazin-1-yl]ethan-1-ol

There total 4 articles about 2-[4-(Pyridin-2-yl)piperazin-1-yl]ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 34803-66-2
1-(2-pyridyl)piperazine

: 540-51-2
2-bromoethanol

: 40004-68-0
2-<4-(pyridin-2-yl)piperazin-1-yl>ethanol

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 80 ℃; for 8h;
DOI:10.1021/jm980622j

Reference yield:

: 34803-66-2
1-(2-pyridyl)piperazine

: 584-08-7
potassium carbonate

: 540-51-2
2-bromoethanol

: 40004-68-0
2-<4-(pyridin-2-yl)piperazin-1-yl>ethanol

Guidance literature:: In N,N-dimethyl-formamide;

Reference yield:

: 109-09-1
2-chloropyridine

: 40004-68-0
2-<4-(pyridin-2-yl)piperazin-1-yl>ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / 8 h / 120 °C

2: 31 percent / K₂CO₃ / dimethylsulfoxide / 8 h / 80 °C

With potassium carbonate; In dimethyl sulfoxide;
DOI:10.1021/jm980622j