(1H-Indol-2-ylmethyl)methylamine

Base Information

Chemical Name:(1H-Indol-2-ylmethyl)methylamine
CAS No.:90888-62-3
Molecular Formula:C₁₀H₁₂N₂
Molecular Weight:160.219
Hs Code.:2933990090
DSSTox Substance ID:DTXSID201301289
Nikkaji Number:J3.455.007G
Mol file:90888-62-3.mol

Synonyms:90888-62-3;(1H-INDOL-2-YLMETHYL)METHYLAMINE;1-(1H-Indol-2-yl)-N-methylmethanamine;(1H-indol-2-ylmethyl)(methyl)amine;[(1H-indol-2-yl)methyl](methyl)amine;(methyl)aminomethyl indole;SCHEMBL1460651;2-(Methylaminomethyl)-1H-indole;RDIZNKNSMGEKKE-UHFFFAOYSA-N;DTXSID201301289;N-Methyl-1H-indole-2-methanamine;N-Methyl-1H-indole-2-methaneamine;AKOS003658167;BS-51269;BB 0220006;CS-0163705;(1H-Indol-2-ylmethyl)methylamine, AldrichCPR;E76798;EN300-102967;Z951182360

Suppliers and Price of (1H-Indol-2-ylmethyl)methylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(1H-Indol-2-ylmethyl)methylamine
50mg
$ 110.00

Matrix Scientific
(1H-Indol-2-ylmethyl)methylamine
500mg
$ 184.00

Crysdot
1-(1H-Indol-2-yl)-N-methylmethanamine 97%
5g
$ 651.00

Chemenu
1-(1H-Indol-2-yl)-N-methylmethanamine 95%+
5g
$ 614.00

American Custom Chemicals Corporation
(1H-INDOL-2-YLMETHYL)METHYLAMINE 95.00%
5G
$ 2392.33

American Custom Chemicals Corporation
(1H-INDOL-2-YLMETHYL)METHYLAMINE 95.00%
2.5G
$ 1771.13

American Custom Chemicals Corporation
(1H-INDOL-2-YLMETHYL)METHYLAMINE 95.00%
1G
$ 1143.61

AK Scientific
(1H-Indol-2-ylmethyl)methylamine
5g
$ 3370.00

Total 5 raw suppliers

Chemical Property of (1H-Indol-2-ylmethyl)methylamine

Chemical Property:

PSA：27.82000
LogP:2.27820
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:160.100048391
Heavy Atom Count:12
Complexity:147

Purity/Quality:

98%min ^*data from raw suppliers

(1H-Indol-2-ylmethyl)methylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNCC1=CC2=CC=CC=C2N1

Technology Process of (1H-Indol-2-ylmethyl)methylamine

There total 4 articles about (1H-Indol-2-ylmethyl)methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 69808-71-5
1H-indole-2-carboxylic acid methylamide

: 90888-62-3
1-(1H-indol-2-yl)-N-methylmethanamine

Guidance literature:: With sodium hydroxide; LiAlH₄; In tetrahydrofuran; methanol; water;

Reference yield:

: 19005-93-7
1H-indol-2-ylcarboxaldehyde

: 74-89-5
methylamine

: 90888-62-3
1-(1H-indol-2-yl)-N-methylmethanamine

Guidance literature:: 1H-indol-2-ylcarboxaldehyde; methylamine; In methanol; at 20 ℃;

With sodium tetrahydroborate; In methanol; at 0 ℃; for 0.166667h;
DOI:10.1021/acs.jmedchem.7b01300

Reference yield:

Indole-2-carboxylic acid: 1477-50-5,1228050-17-6
Indole-2-carboxylic acid

: 90888-62-3
1-(1H-indol-2-yl)-N-methylmethanamine

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 12 h / 20 °C

2: dichloromethane / 0 - 20 °C

3: lithium aluminium tetrahydride / 1,4-dioxane / 0 °C / Inert atmosphere; Reflux

With lithium aluminium tetrahydride; oxalyl dichloride; N,N-dimethyl-formamide; In 1,4-dioxane; dichloromethane;
DOI:10.1055/s-0034-1378921