4-bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one

Base Information

Chemical Name:4-bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
CAS No.:1445993-87-2
Molecular Formula:C15H13BrN2O3S
Molecular Weight:381.25
Hs Code.:
Mol file:1445993-87-2.mol

Synonyms:4-bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one;4-bromo-6-methyl-1-(4-methylbenzenesulfonyl)-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one

Suppliers and Price of 4-bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one 97%
1g
$ 445.00

AK Scientific
4-bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
5g
$ 1751.60

Total 13 raw suppliers

Chemical Property of 4-bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one

Chemical Property:

Boiling Point:564.2±60.0 °C(Predicted)
PKA:-4.40±0.40(Predicted)
PSA：69.45000
Density:1.59±0.1 g/cm3(Predicted)
LogP:3.72870

Purity/Quality:

99%, ^*data from raw suppliers

4-Bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one

There total 19 articles about 4-bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1445993-86-1
4-bromo-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one

: 74-88-4
methyl iodide

: 1445993-87-2
4-bromo-6-methyl-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one

Guidance literature:: 4-bromo-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; for 0.5h; Inert atmosphere;

methyl iodide; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 3h; Inert atmosphere;

Reference yield: 50.0%

: 1361481-63-1
4-bromo-6-methyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one

: 98-59-9
p-toluenesulfonyl chloride

: 1445993-87-2
4-bromo-6-methyl-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one

Guidance literature:: 4-bromo-6-methyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one; With sodium hydride; In tetrahydrofuran; at 0 - 5 ℃; for 0.25h; Inert atmosphere;

p-toluenesulfonyl chloride; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

Reference yield:

: 67443-38-3
5-bromo-2-chloro-3-nitropyridine

: 1445993-87-2
4-bromo-6-methyl-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: tetrahydrofuran / 8 h / -78 - -20 °C

2.1: sodium hydride / tetrahydrofuran / 0.25 h / 0 - 5 °C / Inert atmosphere

2.2: 6 h / 0 - 20 °C

3.1: acetic acid / 48 h / Reflux

4.1: caesium carbonate / N,N-dimethyl-formamide / 3 h / 20 °C

With sodium hydride; caesium carbonate; acetic acid; In tetrahydrofuran; N,N-dimethyl-formamide;