1361481-63-1

Basic information

• Product Name: 4-bromo-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
• Synonyms: 4-bromo-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one;4-bromo-1,6-dihydro-6-methyl-7H-Pyrrolo[2,3-c]pyridin-7-one;4-Bromo-6-methyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one;4-Bromo-6-methyl-1,6-dihydro-pyrrolo[2,3-c]pyridin-7-one
• CAS NO: 1361481-63-1
• Molecular Formula: C₈H₇BrN₂O
• Molecular Weight: 227.05798
• Mol File: 1361481-63-1.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-bromo-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one(1361481-63-1)
• EPA Substance Registry System: 4-bromo-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one(1361481-63-1)

Safety Data

• Hazardous Substances Data: 1361481-63-1(Hazardous Substances Data)

Upstream product

• 917918-81-1 2-(5-bromo-2-methoxy-3-nitropyridin-4-yl)-N,N-dimethylethenamine 
• 1622303-42-7 (E)-5-bromo-4-(2-(dimethylamino)vinyl)-1-methyl-3-nitropyridin-2(1H)-one 
• 1446237-40-6 5-bromo-1,4-dimethyl-3-nitro-1,2-dihydropyridin-2-one 
• 228410-90-0 2-hydroxy-5-bromo-4-methyl-3-nitropyridine 
• 100367-40-6 2-amino-3-nitro-4-methyl-5-bromopyridine 
• 6635-86-5 2-amino-4-methyl-3-nitropyridine 
• 884495-14-1 5-bromo-2-methoxy-4-methyl-3-nitropyridine 
• 1445993-87-2 4-bromo-6-methyl-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one 
• 1445993-86-1 4-bromo-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one 
• 1445993-85-0 4-bromo-7-methoxy-1-(4-methylbenzenesulfonyl)pyrrolo[2,3-c]pyridine 
• 425380-37-6 4-bromo-7-methoxy-1-hydro-pyrrolo[2,3-c]pyridine 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 1445993-87-2 4-bromo-6-methyl-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one 
• 1622302-83-3 4-(tert-butyl)-N-(2-methyl-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)benzamide 
• 1622303-43-8 4-(tert-butyl)-N-(2-methyl-3-(6-methyl-7-oxo-1-tosyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)benzamide 
• 1622303-44-9 4-(tert-butyl)-N-(2-(((tert-butyldimethylsilyl)oxy)methyl)-3-(6-methyl-7-oxo-1-tosyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)benzamide 
• 1622303-45-0 4-(tert-butyl)-N-(2-(hydroxymethyl)-3-(6-methyl-7-oxo-1-tosyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)benzamide 
• 1445993-96-3 ethyl 4-bromo-6-methyl-7-oxo-1-toluenesulfonyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate 

Relevant articles and documents

Nitrogen-containing heterocyclic compound as well as preparation method and application thereof

The invention relates to a nitrogen-containing heterocyclic compound (as shown in a formula I) serving as a BRD4 inhibitor, a pharmaceutical composition containing the nitrogen-containing heterocycliccompound, a preparation method of the nitrogen-containi

COMPOUND FUNCTIONING AS BROMODOMAIN PROTEIN INHIBITOR, AND COMPOSITION

The invention relates to a bromodomain inhibitor. The invention also provides compositions and formulations comprising such compounds, and methods of using and preparing such compounds.

THERAPEUTIC COMPOUNDS AND USES THEREOF

The present invention relates to compounds of formula (I): and to salts thereof, wherein R1-R6 have any of the values defined in the specification, and compositions and uses thereof. The compounds are useful as inhibitors of TAF1. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various TAF1-mediated disorders.