trans-4-Chlorocarbonyl-cyclohexanecarboxylic acid Methyl ester

Base Information

Chemical Name:trans-4-Chlorocarbonyl-cyclohexanecarboxylic acid Methyl ester
CAS No.:183996-94-3
Molecular Formula:C10H16O3
Molecular Weight:184.235
Hs Code.:
Mol file:183996-94-3.mol

Synonyms:trans-4-Chlorocarbonyl-cyclohexanecarboxylic acid Methyl ester;trans-methyl 4-acetylcyclohexanecarboxylate

Suppliers and Price of trans-4-Chlorocarbonyl-cyclohexanecarboxylic acid Methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
trans-Methyl4-acetylcyclohexanecarboxylate 95+%
1g
$ 350.00

Total 12 raw suppliers

Chemical Property of trans-4-Chlorocarbonyl-cyclohexanecarboxylic acid Methyl ester

Chemical Property:

PSA：43.37000
LogP:1.55480

Purity/Quality:

97% ^*data from raw suppliers

trans-Methyl4-acetylcyclohexanecarboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of trans-4-Chlorocarbonyl-cyclohexanecarboxylic acid Methyl ester

There total 6 articles about trans-4-Chlorocarbonyl-cyclohexanecarboxylic acid Methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 75-16-1
methylmagnesium bromide

: C₁₁H₁₉NO₄

: 183996-94-3
trans-4-acetylcyclohexanecarboxylic acid methyl ester

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 1h;
DOI:10.1021/acsmedchemlett.0c00443

Reference yield: 63.0%

: 32529-80-9,36218-60-7
trans-1-chlorocarbonyl-4-(methoxycarbonyl)-cyclohexane

: 544-97-8
dimethyl zinc(II)

: 183996-94-3
trans-4-acetylcyclohexanecarboxylic acid methyl ester

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In toluene; at 0 - 30 ℃; for 3h;

Reference yield:

: 15177-67-0
trans-4-(methoxycarbonyl)cyclohexanecarboxylic acid

: 183996-94-3
trans-4-acetylcyclohexanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 3 h / 50 °C

2: 1.) CuI / 1.) Et₂O, THF, 2 h, 2.) Et₂O, THF, 30 min

With copper(l) iodide; thionyl chloride;
DOI:10.1016/0968-0896(96)00187-3