1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene

Base Information

Chemical Name:1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene
CAS No.:1227160-18-0
Molecular Formula:C10H8BrF3
Molecular Weight:265.073
Hs Code.:2903998090
Mol file:1227160-18-0.mol

Synonyms:1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene;1-(4-Bromophenyl)-1-(trifluoromethyl)cyclopropane;1-Bromo-4-[1-(trifluoromethyl)cycloprop-1-yl]benzene

Suppliers and Price of 1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Bromo-4-(1-(trifluoromethyl)cyclopropyl)benzene
500mg
$ 175.00

SynQuest Laboratories
1-Bromo-4-[1-(trifluoromethyl)cyclopropyl]benzene
1 g
$ 192.00

SynQuest Laboratories
1-Bromo-4-[1-(trifluoromethyl)cyclopropyl]benzene
5 g
$ 672.00

Oakwood
1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene
100g
$ 4995.00

Oakwood
1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene
25g
$ 1490.00

Oakwood
1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene
5g
$ 410.00

Oakwood
1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene
1g
$ 110.00

Oakwood
1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene
250mg
$ 55.00

Matrix Scientific
1-Bromo-4-[1-(trifluoromethyl)cyclopropyl]benzene 95%
500mg
$ 71.00

Matrix Scientific
1-Bromo-4-[1-(trifluoromethyl)cyclopropyl]benzene 95%
1g
$ 109.00

Total 6 raw suppliers

Chemical Property of 1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene

Chemical Property:

PSA：0.00000
LogP:4.04300
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

1-Bromo-4-(1-(trifluoromethyl)cyclopropyl)benzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-Bromo-4-(1-(trifluoromethyl)cyclopropyl)benzene is used as a reactant in the synthesis of a potent, selective T-type calcium channel blocker as drug candidate for treatment of generalized epilepsies.

Technology Process of 1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene

There total 11 articles about 1-Bromo-4-(1-trifluoromethyl-cyclopropyl)-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 883547-73-7
1-phenyl-1-(trifluoromethyl)cyclopropane

: 1227160-18-0
1-bromo-4-(1-(trifluoromethyl)cycloprop-1-yl)benzene

Guidance literature:: With zinc bromide on montmorillonite; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere; Darkness;

Reference yield: 85.0%

: N,N-diethylethanaminium bis[benzene-1,2-diolato^(2-)-kappa²0¹,0²](iodomethyl)silicate

: 136476-20-5
1-bromo-4-(3,3,3-trifluoroprop-1-en-2-yl)benzene

: 1227160-18-0
1-bromo-4-(1-(trifluoromethyl)cycloprop-1-yl)benzene

Guidance literature:: With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; In dimethyl sulfoxide; at 35 ℃; for 3h; Temperature; chemoselective reaction; Inert atmosphere; Sealed tube; Irradiation;
DOI:10.1021/jacs.8b05243

Reference yield: 76.0%

: 887144-97-0
Togni's reagent

: 345965-52-8
1-(4-bromophenyl)cyclopropanecarboxylic acid

: 1227160-18-0
1-bromo-4-(1-(trifluoromethyl)cycloprop-1-yl)benzene

Guidance literature:: With N,N,N′,N′-tetramethyl-N″-tert-butylguanidine; bathophenanthroline; [Ir(3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl]phenyl)₂(4,4'-bis(trifluoromethyl)bipyridine)]PF₆; water; copper(l) cyanide; In ethyl acetate; at 20 ℃; for 12h; Inert atmosphere; Irradiation; Sealed tube;
DOI:10.1021/jacs.8b02650