Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)methoxy]benzoate

Base Information

Chemical Name:Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)methoxy]benzoate
CAS No.:635678-09-0
Molecular Formula:C16H23NO4
Molecular Weight:293.363
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70469963
Wikidata:Q82297907
Mol file:635678-09-0.mol

Synonyms:635678-09-0;methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)methoxy]benzoate;Methyl 3-methoxy-4-((1-methylpiperidin-4-yl)methoxy)benzoate;Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)-methoxy]benzoate;methyl 4-((1-methylpiperidin-4-yl)methoxy)-3-methoxybenzoate;SCHEMBL21473561;DTXSID70469963;MFCD18157679;AKOS015851483;NE-0027;F14186;J-522191;Methyl3-methoxy-4-((1-methylpiperidin-4-yl)methoxy)benzoate

Suppliers and Price of Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)methoxy]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)-methoxy]benzoate >95%
1g
$ 327.00

Matrix Scientific
Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)-methoxy]benzoate >95%
500mg
$ 261.00

Crysdot
Methyl3-methoxy-4-((1-methylpiperidin-4-yl)methoxy)benzoate 95+%
5g
$ 606.00

AK Scientific
Methyl3-methoxy-4-[(1-methylpiperidin-4-yl)-methoxy]benzoate
1g
$ 491.00

Total 5 raw suppliers

Chemical Property of Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)methoxy]benzoate

Chemical Property:

Melting Point:83～85℃
PSA：48.00000
LogP:2.14030
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:293.16270821
Heavy Atom Count:21
Complexity:328

Purity/Quality:

97% ^*data from raw suppliers

Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)-methoxy]benzoate >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC(CC1)COC2=C(C=C(C=C2)C(=O)OC)OC

Technology Process of Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)methoxy]benzoate

There total 6 articles about Methyl 3-methoxy-4-[(1-methylpiperidin-4-yl)methoxy]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 906565-52-4
methyl 3-methoxy-4-(1-tert-butyloxycarbonylpiperidin-4-ylmethoxy)benzoate

: 635678-09-0
methyl 3-methoxy-4-(1-methylpiperidin-4-ylmethoxy)benzoate

Guidance literature:: methyl 3-methoxy-4-(1-tert-butyloxycarbonylpiperidin-4-ylmethoxy)benzoate; With formic acid; at 20 ℃; for 0.005h;

formaldehyd; at 95 ℃; for 0.6h; Inert atmosphere;

Reference yield: 80.0%

: 3-methoxy-4-(piperidin-4-ylmethoxy)-benzoic acid methyl ester

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 635678-09-0
methyl 3-methoxy-4-(1-methylpiperidin-4-ylmethoxy)benzoate

Guidance literature:: With formic acid; In water; at 95 ℃;
DOI:10.1002/jlcr.998

Reference yield:

: 3943-74-6
4-hydroxy-3-methoxybenzoic acid methyl ester

: 635678-09-0
methyl 3-methoxy-4-(1-methylpiperidin-4-ylmethoxy)benzoate

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / triphenylphosphine; diethyl azodicarboxylate / CH₂Cl₂; toluene / 1 h / 20 °C

2: HCl / dioxane / 1 h / 20 °C

3: 80 percent / formic acid / H₂O / 95 °C

With hydrogenchloride; formic acid; triphenylphosphine; diethylazodicarboxylate; In 1,4-dioxane; dichloromethane; water; toluene;
DOI:10.1002/jlcr.998