Carbamic acid, [3-[[(1,1-dimethylethoxy)carbonyl]amino]propyl]-, phenylmethyl ester

Base Information

Chemical Name:Carbamic acid, [3-[[(1,1-dimethylethoxy)carbonyl]amino]propyl]-, phenylmethyl ester
CAS No.:160291-51-0
Molecular Formula:C16H24N2O4
Molecular Weight:308.378
Hs Code.:
DSSTox Substance ID:DTXSID001129879
Mol file:160291-51-0.mol

Synonyms:160291-51-0;Carbamic acid, [3-[[(1,1-dimethylethoxy)carbonyl]amino]propyl]-, phenylmethyl ester;benzyl N-[3-[(2-methylpropan-2-yl)oxycarbonylamino]propyl]carbamate;SCHEMBL13938297;DTXSID001129879;(3-tert-butoxycarbonylaminopropyl)carbamic acid benzyl ester;tert-butyl N-(3-{[(benzyloxy)carbonyl]amino}propyl)carbamate

Suppliers and Price of Carbamic acid, [3-[[(1,1-dimethylethoxy)carbonyl]amino]propyl]-, phenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of Carbamic acid, [3-[[(1,1-dimethylethoxy)carbonyl]amino]propyl]-, phenylmethyl ester

Chemical Property:

PSA：76.66000
LogP:3.60940
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:308.17360725
Heavy Atom Count:22
Complexity:347

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCCNC(=O)OCC1=CC=CC=C1

Technology Process of Carbamic acid, [3-[[(1,1-dimethylethoxy)carbonyl]amino]propyl]-, phenylmethyl ester

There total 5 articles about Carbamic acid, [3-[[(1,1-dimethylethoxy)carbonyl]amino]propyl]-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 75178-96-0
N-Boc-1,3-diaminopropane

: 501-53-1,94274-21-2
benzyl chloroformate

: 160291-51-0
N-(tert-butoxycarbonyl)-N'-(benzyloxycarbonyl)-1,3-propanediamine

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; at 0 - 20 ℃; for 2h;
DOI:10.1016/S0968-0896(01)00356-X

Reference yield: 88.0%

: 181780-34-7
C₁₉H₂₅Cl₃N₂O₆

: 160291-51-0
N-(tert-butoxycarbonyl)-N'-(benzyloxycarbonyl)-1,3-propanediamine

Guidance literature:: With potassium dihydrogenphosphate; zinc; In tetrahydrofuran; for 4h; Ambient temperature;

Reference yield:

: 58885-58-8
N-tert-butoxycarbonyl-3-aminopropanol

: 160291-51-0
N-(tert-butoxycarbonyl)-N'-(benzyloxycarbonyl)-1,3-propanediamine

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / Ph₃P, DEAD / tetrahydrofuran / Ambient temperature

2: 88 percent / Zn, 1.) M aq. KH₂PO₄ / tetrahydrofuran / 4 h / Ambient temperature

With potassium dihydrogenphosphate; triphenylphosphine; zinc; diethylazodicarboxylate; In tetrahydrofuran;