5-broMo-N,3-diMethylpyridin-2-aMine

Base Information

• Chemical Name: 5-broMo-N,3-diMethylpyridin-2-aMine
• CAS No.: 245765-66-6
• Molecular Formula: C7H9BrN2
• Molecular Weight: 201.066
• Hs Code.: 2933399990
• Mol file: 245765-66-6.mol

Synonyms:5-broMo-N,3-diMethylpyridin-2-aMine;2-PyridinaMine, 5-broMo-N,3-diMethyl-;5-BroMo-3-Methyl-2-(MethylaMino)pyridine, 96%;(5-BroMo-3-Methylpyridin-2-yl)MethanaMine

Chemical Property of 5-broMo-N,3-diMethylpyridin-2-aMine

Chemical Property:

• Melting Point: 62-64℃
• Boiling Point: 264.6±40.0 °C(Predicted)
• PKA: 5.31±0.10(Predicted)
• PSA: 24.92000
• Density: 1.494±0.06 g/cm3(Predicted)
• LogP: 2.26720
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99.0% Min ^*data from raw suppliers

5-?romo-N,3-dimethylpyridin-2-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-bromo-N,3-dimethylpyridin-2-amine is a useful research chemical.

Technology Process of 5-broMo-N,3-diMethylpyridin-2-aMine

There total 1 articles about 5-broMo-N,3-diMethylpyridin-2-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromo-2-chloro-3-methylpyridine (29241-60-9) → (5-bromo-6-methylpyridin-2-yl)methylamine (245765-66-6)

Guidance literature:

With methylamine; In water; at 180 ℃; for 4h;

Reference yield: 63.9%

(5-bromo-6-methylpyridin-2-yl)methylamine (245765-66-6) + benzoyl chloride (98-88-4) → N-(5-bromo-3-methylpyridin-2-yl)-N-methylbenzamide (446299-80-5)

Guidance literature:

With triethylamine; In 1,4-dioxane; at 20 - 105 ℃; for 2.33333h;

Reference yield:

(5-bromo-6-methylpyridin-2-yl)methylamine (245765-66-6) + bis(pinacol)diborane (73183-34-3) → N,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (1111637-92-3)

Guidance literature:

With potassium acetate; bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 80 - 90 ℃;

upstream raw materials:

5-bromo-2-chloro-3-methylpyridine

Downstream raw materials:

N-(5-bromo-3-methyl-2-pyridyl)-N,2,2-trimethylpropanamide

N,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

C₃₀H₂₉N₃O₄

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Refernces