alpha-aMine-oMega-propionic acid hexaethylene glycol

Base Information

Chemical Name:alpha-aMine-oMega-propionic acid hexaethylene glycol
CAS No.:905954-28-1
Molecular Formula:C15H31NO8
Molecular Weight:353.413
Hs Code.:2942000090
Mol file:905954-28-1.mol

Synonyms:alpha-aMine-oMega-propionic acid hexaethylene glycol;H2N-PEG6-CH2CH2COOH;α-aMine-ω-propionic acid hexaethylene glycol;1-Amino-3,6,9,12,15,18-hexaoxaheneicosan-21-oic acid;Amino-PEG6-acid;amino-dPEG 6-acid

Suppliers and Price of alpha-aMine-oMega-propionic acid hexaethylene glycol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Amino-3,6,9,12,15,18-hexaoxahenicosan-21-oic Acid
2mg
$ 60.00

TCI Chemical
1-Amino-3,6,9,12,15,18-hexaoxahenicosan-21-oic Acid >95.0%(HPLC)
500mg
$ 473.00

TCI Chemical
1-Amino-3,6,9,12,15,18-hexaoxahenicosan-21-oic Acid >95.0%(HPLC)
100mg
$ 162.00

SynChem
H2N-PEG6-CH2CH2COOH 95%
1 g
$ 510.00

purepeg
α-amine-ω-propionicacidhexaethyleneglycol min.95%
5 g
$ 733.00

Iris Biotech GmbH
H2N-PEG(6)-COOH
5 g
$ 2646.00

Iris Biotech GmbH
H2N-PEG(6)-COOH
250 mg
$ 270.00

Iris Biotech GmbH
H2N-PEG(6)-COOH
1 g
$ 661.50

dPEG
Amino-dPEG??-acid
100 mg
$ 100.00

dPEG
Amino-dPEG??-acid
1000 mg
$ 450.00

Total 42 raw suppliers

Chemical Property of alpha-aMine-oMega-propionic acid hexaethylene glycol

Chemical Property:

Boiling Point:481.0±45.0 °C(Predicted)
PKA:4.28±0.10(Predicted)
PSA：118.70000
Density:1.130±0.06 g/cm3 (20 ºC 760 Torr), Calc.*
LogP:0.21970
Storage Temp.:-20°C

Purity/Quality:

97% ^*data from raw suppliers

1-Amino-3,6,9,12,15,18-hexaoxahenicosan-21-oic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Amino-PEG6-acid is a PEG reagent composing one amine (NH2) and one terminal carboxylic acid group (CO2). The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with activated NHS esters to form a stable amide bond.

Technology Process of alpha-aMine-oMega-propionic acid hexaethylene glycol

There total 6 articles about alpha-aMine-oMega-propionic acid hexaethylene glycol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 882847-34-9,850312-72-0
1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid

: 905954-28-1
3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Guidance literature:: With piperidine; In dichloromethane; at 20 ℃; for 20h;
DOI:10.1016/j.carres.2014.12.010

Reference yield:

: 1286281-32-0,872340-65-3
tert-butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate

: 905954-28-1
3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 1h;

Reference yield:

: 2615-15-8
pentaethylene glycol

: 905954-28-1
3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium / tetrahydrofuran / 20 °C

1.2: 16 h / 20 °C

2.1: triethylamine / dichloromethane / 0 - 20 °C

3.1: sodium azide / N,N-dimethyl-formamide / 50 °C

4.1: triphenylphosphine / tetrahydrofuran; water / 20 °C

5.1: trifluoroacetic acid / dichloromethane / 1 h / 0 - 20 °C

With sodium azide; sodium; triethylamine; triphenylphosphine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;