(1R-cis)-Milnacipran Hydrochloride

Base Information

Chemical Name:(1R-cis)-Milnacipran Hydrochloride
CAS No.:175131-61-0
Molecular Formula:C₁₅H₂₂N₂O*ClH
Molecular Weight:282.813
Hs Code.:
Mol file:175131-61-0.mol

Synonyms:(1R-cis)-Milnacipran Hydrochloride;cis-(-)-Milnacipran Hydrochloride

Suppliers and Price of (1R-cis)-Milnacipran Hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(1R-cis)-MilnacipranHydrochloride
50mg
$ 1230.00

Total 7 raw suppliers

Chemical Property of (1R-cis)-Milnacipran Hydrochloride

Chemical Property:

PSA：46.33000
LogP:3.27370

Purity/Quality:

95% ^*data from raw suppliers

(1R-cis)-MilnacipranHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses The R-enatiomer of Milnacipran (M344600). The (1R-cis)-enatiomer of Milnacipran (M344600). The (1R-cis)-enatiomer of Milnacipran (M344600). A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.

Technology Process of (1R-cis)-Milnacipran Hydrochloride

There total 10 articles about (1R-cis)-Milnacipran Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 96847-54-0,92623-85-3,96847-55-1
(1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide

: 101152-94-7,175131-61-0
(1S,2R)-milnacipran hydrochloride

Guidance literature:: With hydrogenchloride; In water; acetonitrile; Solvent;

Reference yield: 95.0%

: C₁₅H₂₀N₄O

: 86181-08-0,101152-94-7,175131-61-0
cis-(±)-1-phenyl-2-(aminomethyl)-N,N-diethylcyclopropanecarboxamide hydrochloride

Guidance literature:: C₁₅H₂₀N₄O; With palladium 10% on activated carbon; hydrogen; In methanol; for 2h; under 3750.38 Torr;

With hydrogenchloride; In methanol; water;

Reference yield: 94.0%

: 1237261-65-2
(1S,2R)-2-((1,3-dioxoisoindolin-2-yl)methyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide-cyclopropanecarboxamide

: 74-89-5
methylamine

: 101152-94-7,175131-61-0
(1S,2R)-milnacipran hydrochloride

Guidance literature:: (1S,2R)-2-((1,3-dioxoisoindolin-2-yl)methyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide-cyclopropanecarboxamide; methylamine; In 2-methyltetrahydrofuran; water; at 25 ℃; for 3h; Inert atmosphere;

With hydrogenchloride; In methanol; Isopropyl acetate; at 84 - 85 ℃; under 760.051 Torr; pH=1 - 2;