Diethyl 4-(Benzyloxy)pyridine-2,6-dicarboxylate

Base Information

Chemical Name:Diethyl 4-(Benzyloxy)pyridine-2,6-dicarboxylate
CAS No.:18986-14-6
Molecular Formula:C18H19NO5
Molecular Weight:329.353
Hs Code.:2933399090
DSSTox Substance ID:DTXSID90699780
Nikkaji Number:J1.409.509H
Wikidata:Q82630809
Mol file:18986-14-6.mol

Synonyms:18986-14-6;Diethyl 4-(Benzyloxy)pyridine-2,6-dicarboxylate;4-(benzyloxy)-2,6-pyridinedicarboxylic acid diethyl ester;2,6-Pyridinedicarboxylic acid, 4-(phenylmethoxy)-, 2,6-diethyl ester;DIETHYL 4-(PHENYLMETHOXY)-2,6-PYRIDINEDICARBOXYLATE;SCHEMBL112672;DTXSID90699780;DZVFTJRZQKBUDW-UHFFFAOYSA-N;diethyl 4-(benzyloxy)-2,6-pyridinedicarboxylate;J-400870;4-(benzyloxy)pyridin-2,6-dicarboxylic acid diethyl ester

Suppliers and Price of Diethyl 4-(Benzyloxy)pyridine-2,6-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DIETHYL-4-(PHENYLMETHOXY)-2,6-PYRIDINEDICARBOXYLATE 95.00%
5MG
$ 503.89

Total 4 raw suppliers

Chemical Property of Diethyl 4-(Benzyloxy)pyridine-2,6-dicarboxylate

Chemical Property:

Vapor Pressure:1.49E-09mmHg at 25°C
Boiling Point:484.8°C at 760 mmHg
Flash Point:247°C
PSA：74.72000
Density:1.192g/cm³
LogP:3.01400
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:329.12632271
Heavy Atom Count:24
Complexity:382

Purity/Quality:

99% ^*data from raw suppliers

DIETHYL-4-(PHENYLMETHOXY)-2,6-PYRIDINEDICARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=CC(=N1)C(=O)OCC)OCC2=CC=CC=C2

Technology Process of Diethyl 4-(Benzyloxy)pyridine-2,6-dicarboxylate

There total 7 articles about Diethyl 4-(Benzyloxy)pyridine-2,6-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 68631-52-7
4-hydroxypyridine-2,6-dicarboxylic acid diethylester

: 100-39-0
benzyl bromide

: 18986-14-6
4?benzyloxy pyridine?2,6?dicarboxylic acid diethyl ester

Guidance literature:: With potassium carbonate; In acetonitrile; at 82 ℃; for 14h;
DOI:10.1016/j.tet.2010.06.009

Reference yield: 77.0%

: 100-39-0
benzyl bromide

: 115231-56-6
4-oxo-1,4-dihydropyridine-2,6-diethylcarboxylate

: 18986-14-6
4?benzyloxy pyridine?2,6?dicarboxylic acid diethyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 85 ℃; for 4h;
DOI:10.1002/chem.200390122

Reference yield: 54.2%

: 68631-52-7
4-hydroxypyridine-2,6-dicarboxylic acid diethylester

: 100-44-7
benzyl chloride

: 18986-14-6
4?benzyloxy pyridine?2,6?dicarboxylic acid diethyl ester

Guidance literature:: 4-hydroxypyridine-2,6-dicarboxylic acid diethylester; With triethylamine; In tetrahydrofuran; at 20 ℃; for 0.5h;

benzyl chloride; In tetrahydrofuran; Reflux;
DOI:10.1007/s12149-019-01341-0