5-BroMo-1,3-Difluoro-2-(PhenylMethoxy)-Benzene

Base Information

Chemical Name:5-BroMo-1,3-Difluoro-2-(PhenylMethoxy)-Benzene
CAS No.:99045-18-8
Molecular Formula:C13H9BrF2O
Molecular Weight:299.115
Hs Code.:
Mol file:99045-18-8.mol

Synonyms:5-BroMo-1,3-Difluoro-2-(PhenylMethoxy)-Benzene;4-Bromo-2,6-difluoro-1-(benzyloxy)benzene;4-Benzyloxy-3,5-difluorobromobenzene

Suppliers and Price of 5-BroMo-1,3-Difluoro-2-(PhenylMethoxy)-Benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-Bromo-4-benzyloxy-3,5-difluorobenzene 95+%
250mg
$ 68.00

Crysdot
1-Bromo-4-benzyloxy-3,5-difluorobenzene 95+%
5g
$ 610.00

AOBChem
4-Bromo-2,6-difluoro-1-(benzyloxy)benzene 97%
5g
$ 588.00

Alichem
1-Bromo-4-benzyloxy-3,5-difluorobenzene
1g
$ 208.00

Total 9 raw suppliers

Chemical Property of 5-BroMo-1,3-Difluoro-2-(PhenylMethoxy)-Benzene

Chemical Property:

Boiling Point:344.5±37.0 °C(Predicted)
PSA：9.23000
Density:1.505±0.06 g/cm3(Predicted)
LogP:4.30630

Purity/Quality:

97% ^*data from raw suppliers

1-Bromo-4-benzyloxy-3,5-difluorobenzene 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-BroMo-1,3-Difluoro-2-(PhenylMethoxy)-Benzene

There total 3 articles about 5-BroMo-1,3-Difluoro-2-(PhenylMethoxy)-Benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 100-39-0
benzyl bromide

: 104197-13-9
4-bromo-2,6-difluorophenol

: 99045-18-8
1-Bromo-3,5-difluoro-4-(benzyloxy)benzene

Guidance literature:: 4-bromo-2,6-difluorophenol; With potassium carbonate; In acetone; at 70 ℃; for 1h; Sealed tube;

benzyl bromide; In acetone; at 20 - 70 ℃; for 17h; Sealed tube;
DOI:10.1021/acs.jmedchem.5b01963

Reference yield:

: 100-44-7
benzyl chloride

: 104197-13-9
4-bromo-2,6-difluorophenol

: 99045-18-8
1-Bromo-3,5-difluoro-4-(benzyloxy)benzene

Guidance literature:: With potassium carbonate; In demethylformamide;

Reference yield:

: 28177-48-2
2,6-difluorophenol

: 99045-18-8
1-Bromo-3,5-difluoro-4-(benzyloxy)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: bromine; trifluoroacetic acid / 20 °C

2: potassium carbonate / acetonitrile / 20 °C

With bromine; potassium carbonate; trifluoroacetic acid; In acetonitrile;
DOI:10.1139/V10-143