4-Chlorophthalic anhydride

Base Information

• Chemical Name: 4-Chlorophthalic anhydride
• CAS No.: 118-45-6
• Molecular Formula: C8H3ClO3
• Molecular Weight: 182.563
• Hs Code.: 2932999099
• European Community (EC) Number: 204-251-9
• UNII: BPI93D0O61
• DSSTox Substance ID: DTXSID30151993
• Nikkaji Number: J141.265E
• Wikipedia: 4-Chlorophthalic_anhydride
• Wikidata: Q4637112
• Mol file: 118-45-6.mol

Synonyms:4-Chlorophthalic anhydride;118-45-6;5-chloroisobenzofuran-1,3-dione;5-Chloro-2-benzofuran-1,3-dione;4-chlorophthalic acid anhydride;1,3-Isobenzofurandione, 5-chloro-;EINECS 204-251-9;5-chloro-1,3-dihydro-2-benzofuran-1,3-dione;5-chlorophthalic anhydride;MFCD00152354;UNII-BPI93D0O61;BPI93D0O61;5-chloro-isobenzofuran-1,3-dione;EC 204-251-9;4ClPA;4-chloro phthalic anhydride;SCHEMBL79617;P-CHLOROPHTHALIC ANHYDRIDE;DTXSID30151993;BBL028284;STL373477;5-Chloro-2-benzofuran-1,3-dione #;AKOS005255169;PHTHALIC ANHYDRIDE, 4-CHLORO-;CS-W019466;FS-2545;BP-10007;SY002025;C1328;FT-0601240;EN300-97396;A893162;Q4637112;W-108544;3(2H)-Isoquinolinone, 1,4-dihydro-7-methyl-1-thioxo-;4-Chlorophthalic acid anhydride 100 microg/mL in Acetonitrile

Chemical Property of 4-Chlorophthalic anhydride

Chemical Property:

• Appearance/Colour: white crystal powder
• Vapor Pressure: 0.00116mmHg at 25°C
• Melting Point: 96 °C
• Refractive Index: 1.626
• Boiling Point: 299.8 °C at 760 mmHg
• Flash Point: 142.4 °C
• PSA: 43.37000
• Density: 1.594 g/cm³
• LogP: 1.65060
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: soluble in Toluene
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 181.9770716
• Heavy Atom Count: 12
• Complexity: 239

Purity/Quality:

99% ^*data from raw suppliers

4-Chlorophthalic Anhydride ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C1Cl)C(=O)OC2=O
• Uses: 4-chlorophthalic anhydride is an important monomer synthesis of polyimide and polyimide is considered to be the highest tolerance has been industrialized in the polymer and the shape and chemical stability of other materials can not like the outburst strength, wear resistance and extreme temperatures, excellent, has been widely used in aviation, aerospace, microelectronics and atom to the field of high technology. 4- of 4-chlorophthalic anhydride is mainly used in the synthesis of diphenyl ether dianhydride anhydride, two single and two double ether, thioether dianhydride anhydride two, two, and two amine polymerization ring was a series of polyimide engineering plastic with excellent performance. 4- of 4-chlorophthalic anhydride is not only the ideal raw material for the synthesis of various intermediates of polyimide, and can be used as a drug or pesticide.

Technology Process of 4-Chlorophthalic anhydride

There total 23 articles about 4-Chlorophthalic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trimellitic anhydride acid chloride (1204-28-0) → phthalic anhydride (85-44-9) + 4-chlorophthalic anhydride (118-45-6)

Guidance literature:

palladium dichloride; In melt; at 290 ℃; for 2h; Product distribution; other temperatures and other catalysts (Pd/C, Pd(PPh₃)4);

DOI:10.1016/S0040-4039(00)86833-1

Reference yield: 98.0%

4-chlorophthalic acid (89-20-3) → 4-chlorophthalic anhydride (118-45-6)

Guidance literature:

With acetic anhydride; for 3h; Heating;

DOI:10.1021/jo00163a005

Reference yield: 88.0%

1,2,4-trichloro-2,6-dihydrophthalic anhydride → 4-chlorophthalic anhydride (118-45-6)

Guidance literature:

With hydrogenchloride; oxygen; In water; at 100 - 130 ℃; for 5h; Temperature;

upstream raw materials:

phthalic anhydride

tetrachloromethane

4-nitrophthalic anhydride

4-chlorophthalic acid

Downstream raw materials:

5-chloro-2-(methoxycarbonyl)benzoic acid

5-chloro-2-phenylindan-1,3-dione

2-(4-bromo-benzoyl)-4-chloro-benzoic acid

4-chloro-2-(4-chloro-3-methyl-benzoyl)-benzoic acid

Refernces

• 1、 Zweig,Epstein. "-". . p. 3690,3692. Retrieved 1978.
• 2、 -. "A double-(mild imide) preparation method (by machine translation)". Paragraph 0041; 0042. . Retrieved 2018/07/07.
• 3、 -. "PROCESS FOR THE PREPARATION OF ORGANIC HALIDES". Paragraph 00146. . Retrieved 2017/08/01.