5-(Benzyloxy)-1-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid

Base Information

Chemical Name:5-(Benzyloxy)-1-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid
CAS No.:119736-19-5
Molecular Formula:C14H13NO4
Molecular Weight:259.262
Hs Code.:
DSSTox Substance ID:DTXSID301154295
Mol file:119736-19-5.mol

Synonyms:119736-19-5;5-(benzyloxy)-1-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid;5-Benzyloxy-1-Methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid;5-benzyloxy-1-methyl-4-oxo-1,4-dihydro-pyridine-2-carboxylic acid;1,4-Dihydro-1-methyl-4-oxo-5-(phenylmethoxy)-2-pyridinecarboxylic acid;SCHEMBL2115801;IZAWNXNVJUOJCZ-UHFFFAOYSA-N;DTXSID301154295;AKOS005207588;CS-0300673;E89085;EN300-236810;1-methyl-4-oxo-5-phenylmethoxypyridine-2-carboxylic acid;F2158-0181;5-(benzyloxy)-1-methyl-4-oxo-1,4-dihydropyridine-2-carboxylicacid

Suppliers and Price of 5-(Benzyloxy)-1-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 5-(Benzyloxy)-1-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid

Chemical Property:

PSA：68.53000
LogP:1.66250
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:259.08445790
Heavy Atom Count:19
Complexity:433

Purity/Quality:: 98%, 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C=C(C(=O)C=C1C(=O)O)OCC2=CC=CC=C2

Technology Process of 5-(Benzyloxy)-1-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid

There total 5 articles about 5-(Benzyloxy)-1-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1219-33-6
5-(benzyloxy)-4-oxo-4H-pyran-2-carboxylic acid

: 74-89-5
methylamine

: 119736-19-5
2-Pyridinecarboxylic acid, 1,4-dihydro-1-methyl-4-oxo-5-(phenylmethoxy)-

Guidance literature:: In methanol; at 20 ℃; for 16h;

Reference yield:

: 501-30-4,123712-78-7
5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

: 119736-19-5
2-Pyridinecarboxylic acid, 1,4-dihydro-1-methyl-4-oxo-5-(phenylmethoxy)-

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / methanol; water / 0.17 h / Reflux

2: sodium dihydrogenphosphate / acetonitrile; aq. phosphate buffer / pH 6.7

With sodium dihydrogenphosphate; sodium hydroxide; In methanol; aq. phosphate buffer; water; acetonitrile;
DOI:10.1021/jm400560z

Reference yield:

: 100-39-0
benzyl bromide

: 119736-19-5
2-Pyridinecarboxylic acid, 1,4-dihydro-1-methyl-4-oxo-5-(phenylmethoxy)-

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / methanol; water / 0.17 h / Reflux

2: sodium dihydrogenphosphate / acetonitrile; aq. phosphate buffer / pH 6.7

With sodium dihydrogenphosphate; sodium hydroxide; In methanol; aq. phosphate buffer; water; acetonitrile;
DOI:10.1021/jm400560z