4-(4,6-dimorpholino-1,3,5-triazin-2-yl)aniline

Base Information

• Chemical Name: 4-(4,6-dimorpholino-1,3,5-triazin-2-yl)aniline
• CAS No.: 1197159-91-3
• Molecular Formula: C17H22N6O2
• Molecular Weight: 342.401
• Mol file: 1197159-91-3.mol

Synonyms:4-(4,6-dimorpholino-1,3,5-triazin-2-yl)aniline;4-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)benzenamine

Chemical Property of 4-(4,6-dimorpholino-1,3,5-triazin-2-yl)aniline

Chemical Property:

• Melting Point: 266 °C
• PSA: 89.63000
• LogP: 1.50520
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99%, ^*data from raw suppliers

4-(4,6-Dimorpholino-1,3,5-triazin-2-yl)aniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4,6-dimorpholino-1,3,5-triazin-2-yl)aniline

There total 7 articles about 4-(4,6-dimorpholino-1,3,5-triazin-2-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-chloro-4,6-di-morpholin-4-yl-[1,3,5]triazine (7597-22-0) + 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline (214360-73-3) → 4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline (1197159-91-3)

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; for 5h; Reflux;

Reference yield: 77.0%

→ 4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline (1197159-91-3)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; water; at 90 ℃; for 4h;

Reference yield: 45.0%

2-chloro-4,6-di-morpholin-4-yl-[1,3,5]triazine (7597-22-0) + (4-tert-butoxycarbonylaminophenyl)boronic acid pinacol ester (330793-01-6) → 4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline (1197159-91-3)

Guidance literature:

2-chloro-4,6-di-morpholin-4-yl-[1,3,5]triazine; (4-tert-butoxycarbonylaminophenyl)boronic acid pinacol ester; With potassium phosphate; chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); In 1,4-dioxane; water; at 95 ℃; Inert atmosphere;

With hydrogenchloride; In 1,4-dioxane; water; at 60 ℃;

DOI:10.1021/acs.jmedchem.7b00930

upstream raw materials:

2-chloro-4,6-di-morpholin-4-yl-[1,3,5]triazine

4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline

(4-aminophenyl)boronic acid

(4-tert-butoxycarbonylaminophenyl)boronic acid pinacol ester

Downstream raw materials:

1-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]-3-pyridin-4-ylurea

1-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]-3-phenylurea

(2,4-difluorophenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea

1-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]-3-ethylurea

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1197159-91-3 4-(4,6-dimorpholino-1,3,5-triazin-2-yl)aniline

Send

Send

Metric Ton KG G Pound L ML

Send

Send