1-ETHYL-1H-BENZOIMIDAZOL-2-YLAMINE

Base Information

• Chemical Name: 1-ETHYL-1H-BENZOIMIDAZOL-2-YLAMINE
• CAS No.: 1622-58-8
• Molecular Formula: C9H11 N3
• Molecular Weight: 161.206
• Hs Code.: 2933990090
• Mol file: 1622-58-8.mol

Synonyms:Benzimidazole,2-amino-1-ethyl- (6CI,7CI,8CI); 1-Ethyl-1H-benzimidazol-2-ylamine;2-Amino-1-ethylbenzimidazole

Chemical Property of 1-ETHYL-1H-BENZOIMIDAZOL-2-YLAMINE

Chemical Property:

• Vapor Pressure: 8.78E-05mmHg at 25°C
• Melting Point: 158 °C
• Refractive Index: 1.643
• Boiling Point: 340.1°Cat760mmHg
• PKA: 7.06±0.10(Predicted)
• Flash Point: 159.5°C
• PSA: 43.84000
• Density: 1.22g/cm³
• LogP: 2.21960
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

1-ethyl-1H-benzimidazol-2-amine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-ETHYL-1H-BENZOIMIDAZOL-2-YLAMINE

There total 8 articles about 1-ETHYL-1H-BENZOIMIDAZOL-2-YLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-ethyl-1H-benzimidazole-2-sulfonic acid (90331-19-4) → 2-amino-1-ethyl-1H-benzimidazole (1622-58-8)

Guidance literature:

With ammonium acetate; for 3h; Heating;

DOI:10.1007/s10593-006-0112-4

Reference yield: 90.0%

2-amino-1-vinylbenzimidazole (77416-92-3) → 2-amino-1-ethyl-1H-benzimidazole (1622-58-8)

Guidance literature:

With hydrogen; nickel; In ethanol; at 50 - 55 ℃; for 24h; under 22800 Torr;

DOI:10.1007/bf02494645

Reference yield: 65.0%

1H-benzimidazol-2-amine (934-32-7) + ethyl iodide (75-03-6) → 2-amino-1-ethyl-1H-benzimidazole (1622-58-8)

Guidance literature:

With potassium carbonate; potassium hydroxide; In acetone; for 3h; Reflux;

DOI:10.1016/j.ejmech.2013.01.026

upstream raw materials:

2-amino-1-vinylbenzimidazole

1H-benzimidazol-2-amine

1-ethyl-1H-benzimidazole-2-sulfonic acid

1H-benzimidazole-2-sulfonic acid

Downstream raw materials:

1-Ethyl-2-(o-chlorobenzamide)benzimidazole

N-Adamantan-1-yl-2-(3-ethyl-2-imino-2,3-dihydro-benzoimidazol-1-yl)-acetamide; hydrochloride

1,5-diphenyl-4-(2,6-diphenylpyran-4-ylidene)-2-pentene-1,5-dione

C₁₆H₁₆N₄O