2-(4-(4-fluoro-3-(trifluoroMethyl)phenyl)-2-(piperidin-4-yl)-1H-iMidazol-1-yl)-N,N-diMethylethanaMine

Base Information

Chemical Name:2-(4-(4-fluoro-3-(trifluoroMethyl)phenyl)-2-(piperidin-4-yl)-1H-iMidazol-1-yl)-N,N-diMethylethanaMine
CAS No.:1226950-80-6
Molecular Formula:C19H24F4N4
Molecular Weight:384.42
Hs Code.:
Mol file:1226950-80-6.mol

Synonyms:2-(4-(4-fluoro-3-(trifluoroMethyl)phenyl)-2-(piperidin-4-yl)-1H-iMidazol-1-yl)-N,N-diMethylethanaMine;4-[4-Fluoro-3-(trifluoromethyl)phenyl]-N,N-dimethyl-2-(4-piperidinyl)-1H-imidazole-1-ethanamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-(4-fluoro-3-(trifluoroMethyl)phenyl)-2-(piperidin-4-yl)-1H-iMidazol-1-yl)-N,N-diMethylethanaMine

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Technology Process of 2-(4-(4-fluoro-3-(trifluoroMethyl)phenyl)-2-(piperidin-4-yl)-1H-iMidazol-1-yl)-N,N-diMethylethanaMine

There total 16 articles about 2-(4-(4-fluoro-3-(trifluoroMethyl)phenyl)-2-(piperidin-4-yl)-1H-iMidazol-1-yl)-N,N-diMethylethanaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1399035-84-7
2-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-2-(pyridin-4-yl)-1H-imidazol-1-yl}-N,N-dimethylethanamine

: 1226950-80-6
2-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-2-(pyridin-4-yl)-1H-imidazol-1-yl}-N,N-dimethylethanamine

Guidance literature:: With hydrogenchloride; platinum(IV) oxide; hydrogen; In ethanol; water; at 70 ℃; for 24h; under 7240.26 Torr;
DOI:10.1055/s-0031-1290371

Reference yield: 88.0%

: 1226801-75-7
4-(1-(2-(dimethylamino)ethyl)-4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylic acid tert-butyl ester

: 1226950-80-6
2-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-2-(pyridin-4-yl)-1H-imidazol-1-yl}-N,N-dimethylethanamine

Guidance literature:: 4-(1-(2-(dimethylamino)ethyl)-4-(4-fluoro-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)piperidine-1-carboxylic acid tert-butyl ester; With hydrogenchloride; In ethanol; water; at 20 - 55 ℃; for 3.25h;

With sodium hydroxide; In water; at 0 - 5 ℃; for 3h;
DOI:10.1055/s-0033-1338467