methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate

Base Information

Chemical Name:methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate
CAS No.:133747-67-8
Molecular Formula:C12H12ClNO3
Molecular Weight:253.685
Hs Code.:2933790090
Mol file:133747-67-8.mol

Synonyms:methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate

Suppliers and Price of methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate 97%
1g
$ 417.00

Crysdot
Methyl1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate 97%
5g
$ 677.00

Atlantic Research Chemicals
Methyl1-(3-Chlorophenyl)-5-oxopyrrolidine-3-carboxylate 95%
1gm:
$ 208.54

Total 6 raw suppliers

Chemical Property of methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate

Chemical Property:

Boiling Point:450.5±40.0 °C(Predicted)
PKA:-1.99±0.40(Predicted)
PSA：46.61000
Density:1.334±0.06 g/cm3(Predicted)
LogP:1.93090

Purity/Quality:

99%, ^*data from raw suppliers

Methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate

There total 6 articles about methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 67-56-1
methanol

: 92847-41-1
1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylic acid

: 133747-67-8
methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate

Guidance literature:: methanol; With thionyl chloride; at 0 ℃;

1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylic acid; at 0 - 20 ℃;

Reference yield:

: 97-65-4,25119-64-6
2-methylenesuccinic acid

: 133747-67-8
methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 97.7 percent / Heating

2: 90.6 percent / conc. H₂SO₄ / CH₂Cl₂ / Heating

With sulfuric acid; In dichloromethane;
DOI:10.1016/0223-5234(94)90029-9

Reference yield:

: 108-42-9
3-chloro-aniline

: 133747-67-8
methyl 1-(3-chlorophenyl)-5-oxopyrrolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 97.7 percent / Heating

2: 90.6 percent / conc. H₂SO₄ / CH₂Cl₂ / Heating

With sulfuric acid; In dichloromethane;
DOI:10.1016/0223-5234(94)90029-9