tert-butyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octane-5-carboxylate

Base Information

Chemical Name:tert-butyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octane-5-carboxylate
CAS No.:287401-30-3
Molecular Formula:C₁₃H₂₁NO₄
Molecular Weight:255.314
Hs Code.:

Synonyms:2-Oxa-5-azaspiro[3.4]octane-5-carboxylic acid, 1,1-diMethyl-3-oxo-, 1,1-diMethylethyl ester

Suppliers and Price of tert-butyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octane-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octane-5-carboxylate

Chemical Property:

Vapor Pressure:3.93E-05mmHg at 25°C
Boiling Point:352.1°C at 760 mmHg
Flash Point:166.7°C
PSA：55.84000
Density:1.16g/cm³
LogP:2.02940

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octane-5-carboxylate

There total 2 articles about tert-butyl 1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octane-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

: 50903-52-1
(tert-butoxycarbonyl)-L-proline pentafluorophenol ester

: 67-64-1
acetone

: 287401-30-3
tert-butyl-1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octan-5-carboxylate

Guidance literature:: (tert-butoxycarbonyl)-L-proline pentafluorophenol ester; With lithium diisopropyl amide; In tetrahydrofuran; at -90 ℃; for 0.333333h;

acetone; In tetrahydrofuran; at -90 ℃; for 0.5h; Further stages.;
DOI:10.1021/ol0058792

Reference yield: 19.0%

: 64411-39-8
1-tert-butyl 2-phenyl pyrrolidine-1,2-dicarboxylate

: 67-64-1
acetone

: 287401-30-3
tert-butyl-1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octan-5-carboxylate

Guidance literature:: 1-tert-butyl 2-phenyl pyrrolidine-1,2-dicarboxylate; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 1.08333h;

acetone; In tetrahydrofuran; hexane; at -90 - 20 ℃; for 4.83333h; Further stages.;
DOI:10.1021/ol0058792

Reference yield: 100.0%

: 287401-30-3
tert-butyl-1,1-dimethyl-3-oxo-2-oxa-5-azaspiro[3.4]octan-5-carboxylate

: 287401-44-9
tert-butyl-1,1-dimethyl-3,6-dioxo-2-oxa-5-azaspiro[3.4]octan-5-carboxylate

Guidance literature:: With ruthenium trichloride; sodium periodate; In tetrachloromethane; water; acetonitrile; at 20 ℃; for 30h;
DOI:10.1021/ol0058792