1-Chloro-4-(4-iodophenoxy)benzene

Base Information

• Chemical Name: 1-Chloro-4-(4-iodophenoxy)benzene
• CAS No.: 854257-01-5
• Molecular Formula: C12H8ClIO
• Molecular Weight: 330.552
• Hs Code.: 2909309090
• European Community (EC) Number: 691-827-1
• DSSTox Substance ID: DTXSID50598280
• Wikidata: Q82494020
• Mol file: 854257-01-5.mol

Synonyms:854257-01-5;1-chloro-4-(4-iodophenoxy)benzene;4-(4-Chlorophenoxy)iodobenzene;4-Chloro-4'-iododiphenyl ether;1-(4-chlorophenoxy)-4-iodobenzene;4-Chloro-4'-iododiphenyl ether 99%;1-(4-iodophenoxy)-4-chlorobenzene;SCHEMBL3585620;4-(4-clorophenoxy)-iodobenzene;DTXSID50598280;TVALFKNJYMGMJE-UHFFFAOYSA-N;1-chloro-4-(4-iodophenoxyl)benzene;MFCD06796299;AKOS025393445;AB91790;PS-7020;DB-097904;CS-0211564

Chemical Property of 1-Chloro-4-(4-iodophenoxy)benzene

Chemical Property:

• PSA: 9.23000
• LogP: 4.73690
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 329.93084
• Heavy Atom Count: 15
• Complexity: 184

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-4'-iododiphenyl ether 99% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1OC2=CC=C(C=C2)I)Cl

Technology Process of 1-Chloro-4-(4-iodophenoxy)benzene

There total 6 articles about 1-Chloro-4-(4-iodophenoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-amino-4'-chlorodiphenyl ether (101-79-1) → 1-chloro-4-(4-iodophenoxy)benzene (854257-01-5)

Guidance literature:

With hydrogenchloride; potassium iodide; sodium nitrite; In water; at 5 ℃;

DOI:10.1021/ol500696p

Reference yield:

4-chlorodiphenyl ether (7005-72-3) → 1-chloro-4-(4-iodophenoxy)benzene (854257-01-5)

Guidance literature:

With Iodine monochloride; acetic acid;

DOI:10.1021/ja01868a068

Reference yield:

4-phenoxyiodobenzene (2974-94-9) → 1-chloro-4-(4-iodophenoxy)benzene (854257-01-5)

Guidance literature:

With chlorine; acetic acid; Erhitzen des Reaktionsprodukts mit Aethanol;

DOI:10.1021/ja01868a068

upstream raw materials:

ethanol

4-chlorodiphenyl ether

4-phenoxyiodobenzene

4-amino-4'-chlorodiphenyl ether

Downstream raw materials:

C₂₂H₁₈ClNO₃

(4S,5S)-3-(4-(4-chlorophenoxy)phenyl)-5-methyl-4-phenyloxazolidin-2-one

(S)-3-[4-(4-chloro-phenoxy)-phenyl]-4-(3-trifluoromethyl-phenyl)-oxazolidin-2-one

(4S,5R)-ethyl 3-(4-(4-chlorophenoxy)phenyl)-4-(3-fluorophenyl)-2-oxooxazolidine-5-carboxylate