2-amino-5,6-dihydro-4H-1,3-thiazine

Base Information

• Chemical Name: 2-amino-5,6-dihydro-4H-1,3-thiazine
• CAS No.: 30480-64-9
• Molecular Formula: C₄H₈N₂S
• Molecular Weight: 116.187
• Hs Code.: 2934999090
• Mol file: 30480-64-9.mol

Synonyms:2H-1,3-Thiazine,tetrahydro-2-imino- (8CI); 4H-1,3-Thiazine, 2-amino-5,6-dihydro- (6CI);2-Amino-5,6-dihydro-4H-1,3-thiazine

Chemical Property of 2-amino-5,6-dihydro-4H-1,3-thiazine

Chemical Property:

• Vapor Pressure: 0.0505mmHg at 25°C
• Boiling Point: 235.3°Cat760mmHg
• Flash Point: 96.1°C
• PSA: 61.18000
• Density: 1.38g/cm³
• LogP: 1.07620

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-amino-5,6-dihydro-4H-1,3-thiazine

There total 9 articles about 2-amino-5,6-dihydro-4H-1,3-thiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

potassium thioacyanate (333-20-0) + 3-bromopropylamine hydrochloride (5003-71-4) → 2-Iminotetrahydro-1,3-thiazine (30480-64-9)

Guidance literature:

In water; at 90 ℃; for 3h;

DOI:10.1021/jm980721x

Reference yield: 1.5%

Allylthiourea (109-57-9) → 2-amino-4,5-dihydro-6H-1,3-thiazine (30480-64-9) + 5-methyl-4,5-dihydro-1,3-thiazol-2-amine (10416-80-5)

Guidance literature:

With hydrogenchloride; Product distribution; Heating; aq. HBr, aq. H₂SO₄;

DOI:10.1007/BF02290626

Reference yield:

S-aminopropylisothiourea (7320-57-2) → 2-amino-4,5-dihydro-6H-1,3-thiazine (30480-64-9)

Guidance literature:

DOI:10.1021/ja01546a038

upstream raw materials:

homocystamine

potassium cyanide

S-aminopropylisothiourea

tert-butyl-(5,6-dihydro-4H-[1,3]thiazin-2-yl)-amine

Downstream raw materials:

3-methyl-2-phenyl-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine

2-phenyl-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine

2-(4-bromo-phenyl)-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine

4-(4-bromo-phenyl)-7,8-dihydro-6H-[1,3]thiazino[3,2-a][1,3,5]triazine-2-thione