(3-(Benzyloxy)phenyl)methanamine hydrochloride

Base Information

• Chemical Name: (3-(Benzyloxy)phenyl)methanamine hydrochloride
• CAS No.: 104566-41-8
• Molecular Formula: C14H16ClNO
• Molecular Weight: 249.74
• Mol file: 104566-41-8.mol

Synonyms:(3-(Benzyloxy)phenyl)methanamine hydrochloride

Chemical Property of (3-(Benzyloxy)phenyl)methanamine hydrochloride

Chemical Property:

• PSA: 35.25000
• LogP: 4.22660
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

(3-(Benzyloxy)phenyl)methanaminehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3-(Benzyloxy)phenyl)methanamine hydrochloride

There total 4 articles about (3-(Benzyloxy)phenyl)methanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

[3-(benzyloxy)phenyl]methanamine (104566-43-0) → 3-(benzyloxy)benzylamine hydrochloride (104566-41-8)

Guidance literature:

With hydrogenchloride; In dichloromethane; at 20 ℃; for 1h;

Reference yield: 40.0%

diethyl ether (60-29-7,927820-24-4) + 3-Benzyloxybenzaldehyde (1700-37-4) → 3-(benzyloxy)benzylamine hydrochloride (104566-41-8)

Guidance literature:

With sodium borohydrid; In ethanol; ammonia; water;

Reference yield:

4-cyano-2-benzyloxypyridine (61147-43-1) → 3-(benzyloxy)benzylamine hydrochloride (104566-41-8)

Guidance literature:

4-cyano-2-benzyloxypyridine; With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 4.16667h;

With water; ethyl acetate; In diethyl ether;

With hydrogenchloride; In diethyl ether; water;

upstream raw materials:

4-cyano-2-benzyloxypyridine

diethyl ether

3-Benzyloxybenzaldehyde

N-methoxylamine hydrochloride

Downstream raw materials:

4-Chloro-5-(3-benzyloxybenzylamino)-2-i-propyl-3-(2H)pyridazinone

Refernces

• 1、 -. "Compositions and methods of treating cell proliferation disorders". Page/Page column 71. . Retrieved 2008/06/13.
• 2、 -. "3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it". . . Retrieved 2008/06/13.