Ethyl 2-(2-(MethylaMino)pyriMidin-4-yl)-1H-indole-5-carboxylate

Base Information

Chemical Name:Ethyl 2-(2-(MethylaMino)pyriMidin-4-yl)-1H-indole-5-carboxylate
CAS No.:916486-06-1
Molecular Formula:C₁₆H₁₆N₄O₂
Molecular Weight:296.329
Hs Code.:2933990090
Mol file:916486-06-1.mol

Synonyms:Ethyl 2-(2-(MethylaMino)pyriMidin-4-yl)-1H-indole-5-carboxylate;1H-Indole-5-carboxylic acid, 2-[2-(MethylaMino)-4-pyriMidinyl]-, ethyl ester;-1H-indole-5-carboxylate;Ethyl 2-(2-(methylamino);pyrimidin-4-yl)

Suppliers and Price of Ethyl 2-(2-(MethylaMino)pyriMidin-4-yl)-1H-indole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate 95+%
1g
$ 1224.00

Matrix Scientific
Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate 95+%
250mg
$ 490.00

Crysdot
Ethyl2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate 96%
1g
$ 343.00

Chemenu
ethyl2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate 95%+
1g
$ 324.00

American Custom Chemicals Corporation
ETHYL-2-(2-(METHYLAMINO)PYRIMIDIN-4-YL)-1H-INDOLE-5-CARBOXYLATE 95.00%
5MG
$ 501.25

AK Scientific
Ethyl2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate
100mg
$ 167.00

Total 24 raw suppliers

Chemical Property of Ethyl 2-(2-(MethylaMino)pyriMidin-4-yl)-1H-indole-5-carboxylate

Chemical Property:

Boiling Point:552.6±58.0 °C(Predicted)
PKA:13.55±0.30(Predicted)
PSA：83.13000
Density:1.302±0.06 g/cm3(Predicted)
LogP:2.26520
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ethyl 2-(2-(MethylaMino)pyriMidin-4-yl)-1H-indole-5-carboxylate

There total 3 articles about Ethyl 2-(2-(MethylaMino)pyriMidin-4-yl)-1H-indole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 850407-50-0
N-tert-butoxycarbonyl-5-ethoxycarbonylindole

: 916486-06-1
2-(2-methylamino-pyrimidin-4-yl)-1H-indole-5-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium diisopropyl amide / tetrahydrofuran; toluene / 0.08 h / 5 - 10 °C

1.2: 0.5 h / 5 - 10 °C

2.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol / 2 h / 22 - 70 °C

3.1: ethanol / 4 h / 75 - 80 °C

With sodium carbonate; lithium diisopropyl amide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol; toluene;

Reference yield:

: 916486-11-8
2-borono-5-ethoxycarbonyl-indol

: 916486-06-1
2-(2-methylamino-pyrimidin-4-yl)-1H-indole-5-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol / 2 h / 22 - 70 °C

2: ethanol / 4 h / 75 - 80 °C

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol;