5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 6-[2-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl] 5-(1,1-diMethylethyl) ester, (6S)-

Base Information

Chemical Name:5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 6-[2-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl] 5-(1,1-diMethylethyl) ester, (6S)-
CAS No.:1499193-61-1
Molecular Formula:C₂₇H₂₆BrF₂NO₅
Molecular Weight:562.408
Hs Code.:
Mol file:1499193-61-1.mol

Synonyms:5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 6-[2-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl] 5-(1,1-diMethylethyl) ester, (6S)-

Suppliers and Price of 5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 6-[2-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl] 5-(1,1-diMethylethyl) ester, (6S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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ChemScene
5-Azaspiro[2.4]heptane-5,6-dicarboxylicacid,6-[2-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl]5-(1,1-dimethylethyl)ester,(6S)-
1g
$ 450.00

Total 5 raw suppliers

Chemical Property of 5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 6-[2-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl] 5-(1,1-diMethylethyl) ester, (6S)-

Chemical Property:

Boiling Point:617.5±55.0 °C(Predicted)
PKA:-3.06±0.40(Predicted)
PSA：72.91000
Density:1.52±0.1 g/cm3(Predicted)
LogP:6.02300

Purity/Quality:

≥95% ^*data from raw suppliers

5-Azaspiro[2.4]heptane-5,6-dicarboxylicacid,6-[2-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl]5-(1,1-dimethylethyl)ester,(6S)- ^*data from reagent suppliers

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Technology Process of 5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 6-[2-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl] 5-(1,1-diMethylethyl) ester, (6S)-

There total 16 articles about 5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 6-[2-(7-broMo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl] 5-(1,1-diMethylethyl) ester, (6S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1129634-44-1,1454843-77-6,1454843-78-7
(6S)-5-[(tert-butoxy)carbonyl]-5-azaspiro[2.4]heptane-6-carboxylic acid

: 1378387-81-5
1-(7-bromo-9,9-difluoro-9-hydrofluoren-2-yl)-2-chloroethanone

: 1499193-61-1
(S)-6-(2-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl) 5-tert-butyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate

Guidance literature:: (6S)-5-[(tert-butoxy)carbonyl]-5-azaspiro[2.4]heptane-6-carboxylic acid; With potassium carbonate; In acetone; at 35 ℃; for 3h; Inert atmosphere;

1-(7-bromo-9,9-difluoro-9-hydrofluoren-2-yl)-2-chloroethanone; With sodium iodide; In acetone; at 35 ℃; for 3h;