Methyl 3-amino-3-(3-fluorophenyl)propanoate HCl

Base Information

Chemical Name:Methyl 3-amino-3-(3-fluorophenyl)propanoate HCl
CAS No.:277745-43-4
Molecular Formula:C₁₀H₁₂FNO₂
Molecular Weight:0
Hs Code.:
Mol file:277745-43-4.mol

Synonyms:Methyl 3-amino-3-(3-fluorophenyl)propanoate HCl

Suppliers and Price of Methyl 3-amino-3-(3-fluorophenyl)propanoate HCl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of Methyl 3-amino-3-(3-fluorophenyl)propanoate HCl

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Methyl 3-amino-3-(3-fluorophenyl)propanoate HCl

There total 2 articles about Methyl 3-amino-3-(3-fluorophenyl)propanoate HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 67-56-1
methanol

: 117391-51-2,723284-81-9
(+/-)-3-amino-3-(3-fluorophenyl)propanoic acid

: 277745-43-4
3-amino-3-(3-fluorophenyl)propionic acid methyl ester

Guidance literature:: With hydrogenchloride; In water; for 12h; Reflux;
DOI:10.1002/adsc.200900676

Reference yield:

: 456-48-4
3-Fluorobenzaldehyde

: 277745-43-4
3-amino-3-(3-fluorophenyl)propionic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium acetate / ethanol / 78 °C

2: thionyl chloride / 6 h / 65 °C

With thionyl chloride; ammonium acetate; In ethanol;
DOI:10.1016/j.bmc.2014.11.036

Reference yield:

: 38422-62-7
5-(tert-butyl)-2-methylfuran-3-carboxylic acid

: 277745-43-4
3-amino-3-(3-fluorophenyl)propionic acid methyl ester

: C₂₀H₂₄FNO₄

Guidance literature:: 5-(tert-butyl)-2-methylfuran-3-carboxylic acid; With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

3-amino-3-(3-fluorophenyl)propionic acid methyl ester; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 30 ℃; for 2h;
DOI:10.1016/j.bmc.2014.11.036