Methyl 3-AMinocyclopentanecarboxylate Hydrochloride

Base Information

• Chemical Name: Methyl 3-AMinocyclopentanecarboxylate Hydrochloride
• CAS No.: 1398534-59-2
• Molecular Formula: C₇H₁₃NO₂*ClH
• Molecular Weight: 179.647
• Hs Code.: 2922499990
• Mol file: 1398534-59-2.mol

Synonyms:Methyl 3-AMinocyclopentanecarboxylate Hydrochloride;Cyclopentanecarboxylic acid, 3-amino-, methyl ester hydrochloride

Chemical Property of Methyl 3-AMinocyclopentanecarboxylate Hydrochloride

Chemical Property:

• PSA: 52.32000
• LogP: 1.78910
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

Cyclopentanecarboxylicacid,3-amino-,methylesterhydrochloride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Methyl 3-aminocyclopentanecarboxylate HCl

Technology Process of Methyl 3-AMinocyclopentanecarboxylate Hydrochloride

There total 17 articles about Methyl 3-AMinocyclopentanecarboxylate Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + (1S,3R)-3-aminocyclopentanecarboxylic acid (71830-07-4) → (1S,3R)-3-amino-cyclopentanecarboxylic acid methyl ester hydrochloride (180323-49-3,222530-45-2,1398534-59-2,222530-29-2)

Guidance literature:

With thionyl chloride; at 18 - 25 ℃; for 2.5h; Cooling with acetone-ice; Heating / reflux;

Reference yield: 100.0%

methanol (67-56-1) + (1R,3S)-3-aminocyclopentanecarboxylic acid (71830-08-5) → (1R,3S)-methyl 3-aminocyclopentanecarboxylate hydrochloride (180323-49-3,222530-45-2,1398534-59-2,222530-29-2)

Guidance literature:

With thionyl chloride; at 0 - 65 ℃; for 20h;

Reference yield: 98.0%

methanol (67-56-1) + (1R,3S)-3-aminocyclopentanecarboxylic acid hydrochloride (1203306-05-1,1392803-15-4,19042-35-4,147780-44-7) → (1R,3S)-methyl 3-aminocyclopentanecarboxylate hydrochloride (180323-49-3,222530-45-2,1398534-59-2,222530-29-2)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃; Inert atmosphere;

upstream raw materials:

methanol

(1R,3S)-3-aminocyclopentanecarboxylic acid hydrochloride

(1S,4R)-N-(9-Phenylfluoren-9-yl)-2-azabicyclo<2.2.1>heptan-3-one

(1R,3S)-3-aminocyclopentanecarboxylic acid

Refernces

• 1、 -. "HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS". Page/Page column 131; 132. . Retrieved 2020/07/14.
• 2、 -. "METHODS OF RATIONAL NICOTINE HAPTEN DESIGN AND USES THEREOF". Paragraph 0094. . Retrieved 2017/01/19.