4-(N-fluorenylmethoxycarbonyl)amino-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene

Base Information

Chemical Name:4-(N-fluorenylmethoxycarbonyl)amino-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene
CAS No.:381230-97-3
Molecular Formula:C₃₇H₃₃Cl₂NO₈
Molecular Weight:690.577
Hs Code.:

Synonyms:4-(N-fluorenylmethoxycarbonyl)amino-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene

Suppliers and Price of 4-(N-fluorenylmethoxycarbonyl)amino-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(N-fluorenylmethoxycarbonyl)amino-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(N-fluorenylmethoxycarbonyl)amino-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene

There total 3 articles about 4-(N-fluorenylmethoxycarbonyl)amino-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 154023-65-1
3,3'-dichloro-4,4'-dimethoxy-5,5'-bis(methoxycarbonyl)benzophenone

: 267410-86-6
3-(N-(9-fluorenylmethoxycarbonyl)amino)propionaldehyde

: 381230-97-3
4-(N-fluorenylmethoxycarbonyl)amino-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene

Guidance literature:: With tetrachlorobis(tetrahydrofuran)titanium(IV); zinc; In tetrahydrofuran; for 2.5h; Heating;
DOI:10.1016/S0968-0896(01)00152-3

Reference yield:

: 35737-10-1
N-Fmoc-β-alanine

: 381230-97-3
4-(N-fluorenylmethoxycarbonyl)amino-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl chloride; N,N-dimethylformamide / tetrahydrofuran / 2 h / 20 °C

2: 1.27 g / (Ph₃P)4Pd; tributyltin hydride / tetrahydrofuran / 1 h / 20 °C

3: 72 percent / TiCl₄*2THF complex; zinc / tetrahydrofuran / 2.5 h / Heating

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrachlorobis(tetrahydrofuran)titanium(IV); oxalyl dichloride; tri-n-butyl-tin hydride; N,N-dimethyl-formamide; zinc; In tetrahydrofuran; 3: McMurry coupling;
DOI:10.1016/S0968-0896(01)00152-3

Reference yield:

: 183720-79-8
9H-fluoren-9-ylmethyl N-(3-chloro-3-oxo-propyl)carbamate

: 381230-97-3
4-(N-fluorenylmethoxycarbonyl)amino-3',3''-dichloro-4',4''-dimethoxy-5',5''-bis(methoxycarbonyl)-1,1-diphenyl-1-butene

Guidance literature:: Multi-step reaction with 2 steps

1: 1.27 g / (Ph₃P)4Pd; tributyltin hydride / tetrahydrofuran / 1 h / 20 °C

2: 72 percent / TiCl₄*2THF complex; zinc / tetrahydrofuran / 2.5 h / Heating

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrachlorobis(tetrahydrofuran)titanium(IV); tri-n-butyl-tin hydride; zinc; In tetrahydrofuran; 2: McMurry coupling;
DOI:10.1016/S0968-0896(01)00152-3