2-acetyloxy-3-chloropyridine

Base Information

• Chemical Name: 2-acetyloxy-3-chloropyridine
• CAS No.: 98273-80-4
• Molecular Formula: C₇H₆ClNO₂
• Molecular Weight: 171.583
• Mol file: 98273-80-4.mol

Synonyms:2-acetyloxy-3-chloropyridine

Chemical Property of 2-acetyloxy-3-chloropyridine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-acetyloxy-3-chloropyridine

There total 1 articles about 2-acetyloxy-3-chloropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-Chloropyridine (626-60-8) → 2-acetyloxy-3-chloropyridine (98273-80-4) + 2-bromo-3-chloropyridine (96424-68-9)

Guidance literature:

With acetyl hypofluorite; 1,1-dibromomethane; In trichlorofluoromethane; Ambient temperature;

DOI:10.1021/jo00240a047

Reference yield: 59.0%

1-(4-methylbenzensulfonyl)-4-phenyl-1H-1,2,3-triazole (884866-01-7) + 2-acetyloxy-3-chloropyridine (98273-80-4) → (Z)-N-(2-(3-chloro-2-oxopyridin-1(2H)-yl)-2-phenylvinyl)-N-tosylacetamide

Guidance literature:

With bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; In Cyclopentane; benzene; at 110 ℃; for 4h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.0c03533

Reference yield:

2-acetyloxy-3-chloropyridine (98273-80-4) → 3-chloro-2-hydroxypyridine (13466-35-8)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/jo01105a008

upstream raw materials:

3-Chloropyridine

Downstream raw materials:

3-chloro-2-hydroxypyridine

2,3-dichloro-pyridine

Refernces