3(RS)--2-benzylpropanoic acid

Base Information

• Chemical Name: 3(RS)--2-benzylpropanoic acid
• CAS No.: 96866-15-8
• Molecular Formula: C₁₈H₁₉NO₄
• Molecular Weight: 313.353

Synonyms:3(RS)--2-benzylpropanoic acid

Chemical Property of 3(RS)--2-benzylpropanoic acid

Chemical Property:

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Technology Process of 3(RS)--2-benzylpropanoic acid

There total 3 articles about 3(RS)--2-benzylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-(R,S)-benzyl-3-benzyloxyamino-propionic acid (96866-14-7) → 3(RS)--2-benzylpropanoic acid (96866-15-8)

Guidance literature:

With acetic anhydride; In formic acid; water;

Reference yield:

2-Benzyl-2-propenoic acid (5669-19-2) → 3(RS)--2-benzylpropanoic acid (96866-15-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 57 percent / ethanol / 168 h / Heating

2: 98 percent / acetic anhydride / 3 h / 0 °C

With acetic anhydride; In ethanol;

DOI:10.1021/jm00147a007

Reference yield:

N-benzyloxyamine (622-33-3) → 3(RS)--2-benzylpropanoic acid (96866-15-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 57 percent / ethanol / 168 h / Heating

2: 98 percent / acetic anhydride / 3 h / 0 °C

With acetic anhydride; In ethanol;

DOI:10.1021/jm00147a007

upstream raw materials:

N-benzyloxyamine

2-Benzyl-2-propenoic acid

2-(R,S)-benzyl-3-benzyloxyamino-propionic acid

Downstream raw materials:

(S)-2-((S)-2-{2-[(Benzyloxy-formyl-amino)-methyl]-3-phenyl-propionylamino}-4-methyl-pentanoylamino)-3-phenyl-propionic acid benzyl ester

(7-{2-[(benzyloxy-formyl-amino)-methyl]-3-phenyl-propionylamino}-8-oxo-7,8-dihydro-6H-5-oxa-9-aza-benzocyclohepten-9-yl)-acetic acid benzyl ester

2S-[2-(R,S)-Benzyl-3-(benzyloxy-formyl-amino)-propionylamino]-3-phenyl Propionic Acid Cyclopentyl Ester

N-[3(RS)-(N-formyl-N-hydroxyamino)-1-oxo-2-benzylpropyl]glycine benzylamide

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