2,4'-Dihydroxydiphenylmethane

Base Information

• Chemical Name: 2,4'-Dihydroxydiphenylmethane
• CAS No.: 2467-03-0
• Molecular Formula: C13H12 O2
• Molecular Weight: 200.237
• Hs Code.: 2907299090
• European Community (EC) Number: 219-579-8
• NSC Number: 36395
• UNII: LIX5YMK20B
• DSSTox Substance ID: DTXSID2044890
• Nikkaji Number: J80.495I
• Wikidata: Q27283009
• Metabolomics Workbench ID: 130669
• ChEMBL ID: CHEMBL3187039
• Mol file: 2467-03-0.mol

Synonyms:(2,4'-dihydroxyphenyl)methane;2,4'-bisphenol F;ortho, para-bisphenol F

Chemical Property of 2,4'-Dihydroxydiphenylmethane

Chemical Property:

• Melting Point: 119 °C
• Boiling Point: 376°Cat760mmHg
• PKA: 10.15±0.30(Predicted)
• Flash Point: 184.9°C
• PSA: 40.46000
• Density: 1.208g/cm³
• LogP: 2.68860
• Storage Temp.: 2-8°C
• Solubility.: Acetonitrile (Slightly), DMSO (Slightly)
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 200.083729621
• Heavy Atom Count: 15
• Complexity: 185

Purity/Quality:

99.0% ^*data from raw suppliers

2,4''-Dihydroxydiphenylmethane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 36/37/38-62-43-41-37
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)CC2=CC=C(C=C2)O)O
• Description: o-p'-Bisphenol F is allergenic components of phenol-formaldehyde resins resol-type.
• Uses: 2,4''-Dihydroxydiphenylmethane can be used in anisotropically conductive paste containing thermosetting compd. and solder particles with improved reliability.

Technology Process of 2,4'-Dihydroxydiphenylmethane

There total 22 articles about 2,4'-Dihydroxydiphenylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.19%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + phenol (108-95-2,27073-41-2) → Bis(2-hydroxyphenyl)methane (2467-02-9) + 2-[(4-hydroxyphenyl)methyl]phenol (2467-03-0) + bis-(4-hydroxyphenyl)methane (620-92-8)

Guidance literature:

phenol; With catalyst with modified organic framework formed from chromium trioxide and phosphotungstic acid; at 80 ℃; for 0.25h;

formaldehyd; In water; at 80 ℃; for 0.5h; Concentration; Time; Temperature; Reagent/catalyst;

Reference yield:

POMM5 (13352-76-6) + phenol (108-95-2,27073-41-2) → Bis(2-hydroxyphenyl)methane (2467-02-9) + 2-[(4-hydroxyphenyl)methyl]phenol (2467-03-0) + bis-(4-hydroxyphenyl)methane (620-92-8)

Guidance literature:

With phosphoric acid; In water; at 80 ℃; for 4h; Overall yield = 74.8 %;

Reference yield:

CH3-(OCH2)6-OCH3 (13352-77-7) + phenol (108-95-2,27073-41-2) → Bis(2-hydroxyphenyl)methane (2467-02-9) + 2-[(4-hydroxyphenyl)methyl]phenol (2467-03-0) + bis-(4-hydroxyphenyl)methane (620-92-8)

Guidance literature:

With phosphoric acid; In water; at 80 ℃; for 4h; Overall yield = 66.2 %;

upstream raw materials:

2,4'-diaminodiphenylmethane

2',6'-dibromo-4-chloro-2,4'-methanediyl-di-phenol

formaldehyd

phenol

Downstream raw materials:

(2-hydroxy-3,5-bis-hydroxymethyl-phenyl)-(4-hydroxy-3,5-bis-hydroxymethyl-phenyl)-methane

4,6,2',6'-tetrabromo-2,4'-methanediyl-di-phenol

(2-acetoxy-phenyl)-(4-acetoxy-phenyl)-methane

(2-ethoxy-phenyl)-(4-ethoxy-phenyl)methane

Refernces

• 1、 -. "For simultaneous preparation14 C mark F isomer of bisphenol (by machine translation)". Paragraph 0038-0039. . Retrieved 2017/08/29.
• 2、 -. "A modified metal organic framework of phosphotungstic acid to bisphenol F catalytic synthesis method". Paragraph 0028; 0041; 0042; 0045; 0046; 0047; 0048. . Retrieved 2016/10/20.