(E)-N,N'-bis(tert-butyloxycarbonyl)-N,N'-bis[(4-iodophenyl)sulfonyl]-2-butene-1,4-diamine

Base Information

• Chemical Name: (E)-N,N'-bis(tert-butyloxycarbonyl)-N,N'-bis[(4-iodophenyl)sulfonyl]-2-butene-1,4-diamine
• CAS No.: 335004-24-5
• Molecular Formula: C₂₆H₃₂I₂N₂O₈S₂
• Molecular Weight: 818.49
• Mol file: 335004-24-5.mol

Synonyms:(E)-N,N'-bis(tert-butyloxycarbonyl)-N,N'-bis[(4-iodophenyl)sulfonyl]-2-butene-1,4-diamine

Chemical Property of (E)-N,N'-bis(tert-butyloxycarbonyl)-N,N'-bis[(4-iodophenyl)sulfonyl]-2-butene-1,4-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-N,N'-bis(tert-butyloxycarbonyl)-N,N'-bis[(4-iodophenyl)sulfonyl]-2-butene-1,4-diamine

There total 4 articles about (E)-N,N'-bis(tert-butyloxycarbonyl)-N,N'-bis[(4-iodophenyl)sulfonyl]-2-butene-1,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(E)-1,4-dibromobutene (821-06-7) + N-(tert-butyloxycarbonyl)-4-iodobenzenesulfonamide (154377-75-0) → (E)-N,N'-bis(tert-butyloxycarbonyl)-N,N'-bis[(4-iodophenyl)sulfonyl]-2-butene-1,4-diamine (335004-24-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1002/1099-0690(200101)2001:2<329::aid-ejoc329>3.0.co;2-n

Reference yield:

iodobenzene (591-50-4) → (E)-N,N'-bis(tert-butyloxycarbonyl)-N,N'-bis[(4-iodophenyl)sulfonyl]-2-butene-1,4-diamine (335004-24-5)

Guidance literature:

Multi-step reaction with 4 steps

1: chlorosulfonic acid / 20 °C

2: NH₃

3: 90 percent / Et₃N; DMAP / CH₂Cl₂

4: 92 percent / K₂CO₃ / dimethylformamide / 20 °C

With chlorosulfonic acid; dmap; ammonia; potassium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/1099-0690(200101)2001:2<329::aid-ejoc329>3.0.co;2-n

Reference yield:

p-Iodobenzenesulfonyl chloride (98-61-3) → (E)-N,N'-bis(tert-butyloxycarbonyl)-N,N'-bis[(4-iodophenyl)sulfonyl]-2-butene-1,4-diamine (335004-24-5)

Guidance literature:

Multi-step reaction with 3 steps

1: NH₃

2: 90 percent / Et₃N; DMAP / CH₂Cl₂

3: 92 percent / K₂CO₃ / dimethylformamide / 20 °C

With dmap; ammonia; potassium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/1099-0690(200101)2001:2<329::aid-ejoc329>3.0.co;2-n

upstream raw materials:

(E)-1,4-dibromobutene

N-(tert-butyloxycarbonyl)-4-iodobenzenesulfonamide

iodobenzene

4-iodo-benzenesulfonamide

Downstream raw materials:

(E)-N,N'-bis[(4-iodophenyl)sulfonyl]-2-butene-1,4-diamine

(E,E,E)-1,14-dibromo-N,N'-bis[(4-iodophenyl)sulfonyl]-5,10-diazatetradeca-2,7,12-triene