N-(4-bromo-2-chloro-5-trifluoromethoxy-phenyl)-6-fluoro-nicotinamide

Base Information

Chemical Name:N-(4-bromo-2-chloro-5-trifluoromethoxy-phenyl)-6-fluoro-nicotinamide
CAS No.:1374892-55-3
Molecular Formula:C₁₃H₆BrClF₄N₂O₂
Molecular Weight:413.553
Hs Code.:

Synonyms:N-(4-bromo-2-chloro-5-trifluoromethoxy-phenyl)-6-fluoro-nicotinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-bromo-2-chloro-5-trifluoromethoxy-phenyl)-6-fluoro-nicotinamide

Chemical Property:

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Technology Process of N-(4-bromo-2-chloro-5-trifluoromethoxy-phenyl)-6-fluoro-nicotinamide

There total 3 articles about N-(4-bromo-2-chloro-5-trifluoromethoxy-phenyl)-6-fluoro-nicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 115844-00-3
4-bromo-2-chloro-5-(trifluoromethoxy)phenylamine

: 65352-94-5
6-fluoronicotinoyl chloride

: 1374892-55-3
N-(4-bromo-2-chloro-5-trifluoromethoxy-phenyl)-6-fluoro-nicotinamide

Guidance literature:: With N,N-dimethyl acetamide; In dichloromethane;

Reference yield:

: 65352-94-5
6-fluoronicotinoyl chloride

: 1374892-55-3
N-(4-bromo-2-chloro-5-trifluoromethoxy-phenyl)-6-fluoro-nicotinamide

Guidance literature:: With 2,4-dichlorophenoxyacetic acid dimethylamine; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

Reference yield:

: 116369-25-6
4-bromo-3-(trifluoromethoxy)phenylamine

: 1374892-55-3
N-(4-bromo-2-chloro-5-trifluoromethoxy-phenyl)-6-fluoro-nicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1: N-chloro-succinimide / acetonitrile / 60 °C

2: N,N-dimethyl acetamide / dichloromethane

With N-chloro-succinimide; N,N-dimethyl acetamide; In dichloromethane; acetonitrile;