(+/-)-α-<2-ethyl>-2-chlorophenylacetonitrile

Base Information

• Chemical Name: (+/-)-α-<2-ethyl>-2-chlorophenylacetonitrile
• CAS No.: 68284-62-8
• Molecular Formula: C₁₆H₂₃ClN₂
• Molecular Weight: 278.825

Synonyms:(+/-)-α-<2-ethyl>-2-chlorophenylacetonitrile

Chemical Property of (+/-)-α-<2-ethyl>-2-chlorophenylacetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (+/-)-α-<2-ethyl>-2-chlorophenylacetonitrile

There total 2 articles about (+/-)-α-<2-ethyl>-2-chlorophenylacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2-Chlorophenylacetonitrile (2856-63-5) + (2-chloroethyl)-diisopropylamine (96-79-7) → (+/-)-α-<2-ethyl>-2-chlorophenylacetonitrile (68284-62-8)

Guidance literature:

With sodium amide; In toluene; at 80 - 85 ℃; for 0.5h;

DOI:10.1021/jm00184a008

Reference yield:

→ (+/-)-α-<2-ethyl>-2-chlorophenylacetonitrile (68284-62-8)

Guidance literature:

Chloracetonitril, Chlor-N.N-diisopropylethylamin;

Reference yield: 78.0%

methanol (67-56-1) + (+/-)-α-<2-ethyl>-2-chlorophenylacetonitrile (68284-62-8) → (+/-)-methyl α-<2-ethyl>-2-chlorobenzeneacetate (116078-69-4)

Guidance literature:

With sulfuric acid; for 6h; Heating;

DOI:10.1021/jm00119a017

upstream raw materials:

2-Chlorophenylacetonitrile

(2-chloroethyl)-diisopropylamine

Downstream raw materials:

2-(2-Chloro-phenyl)-4-diisopropylamino-2-(2-morpholin-4-yl-ethyl)-butyronitrile

α-[2-[bis(1-methylethyl)amino]ethyl]-α-(2-chlorophenyl)-2-pyridinepropanenitrile

(+/-)-methyl α-<2-ethyl>-2-chlorobenzeneacetate

(+/-)-1-<5--3-(2-chlorophenyl)-3-cyano-1-oxopentyl>piperidine

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