ethyl (RS)-N-[(EZ)-4-(4-chlorophenyl)-3-cyano-7-methoxy-4H-chromen-2-yl]formimidate

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Chemical Name:ethyl (RS)-N-[(EZ)-4-(4-chlorophenyl)-3-cyano-7-methoxy-4H-chromen-2-yl]formimidate
CAS No.:1403826-32-3
Molecular Formula:C₂₀H₁₇ClN₂O₃
Molecular Weight:368.82
Hs Code.:

Synonyms:ethyl (RS)-N-[(EZ)-4-(4-chlorophenyl)-3-cyano-7-methoxy-4H-chromen-2-yl]formimidate

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Chemical Property of ethyl (RS)-N-[(EZ)-4-(4-chlorophenyl)-3-cyano-7-methoxy-4H-chromen-2-yl]formimidate

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Technology Process of ethyl (RS)-N-[(EZ)-4-(4-chlorophenyl)-3-cyano-7-methoxy-4H-chromen-2-yl]formimidate

There total 2 articles about ethyl (RS)-N-[(EZ)-4-(4-chlorophenyl)-3-cyano-7-methoxy-4H-chromen-2-yl]formimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 326918-74-5
(RS)-2-amino-4-(4-chlorophenyl)-7-methoxy-4H-chromene-3-carbonitrile

: 122-51-0
orthoformic acid triethyl ester

: 1403826-32-3
ethyl (RS)-N-[(EZ)-4-(4-chlorophenyl)-3-cyano-7-methoxy-4H-chromen-2-yl]formimidate

Guidance literature:: for 4h; Reflux;
DOI:10.1016/j.ejmech.2012.11.011

Reference yield:

: 130944-03-5
2-Amino-4-(4-chloro-phenyl)-7-hydroxy-4H-chromene-3-carbonitrile

: 1403826-32-3
ethyl (RS)-N-[(EZ)-4-(4-chlorophenyl)-3-cyano-7-methoxy-4H-chromen-2-yl]formimidate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hydroxide / ethanol / 1 h / 20 °C

1.2: 24 h / Reflux

2.1: 4 h / Reflux

With potassium hydroxide; In ethanol;
DOI:10.1016/j.ejmech.2012.11.011