1,3-Difluoroadamantane

Base Information

• Chemical Name: 1,3-Difluoroadamantane
• CAS No.: 54043-61-7
• Molecular Formula: C₁₀H₁₄F₂
• Molecular Weight: 172.218
• Mol file: 54043-61-7.mol

Synonyms:1,3-Difluoroadamantane

Chemical Property of 1,3-Difluoroadamantane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-Difluoroadamantane

There total 2 articles about 1,3-Difluoroadamantane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

adamantane (281-23-2) → 1-adamantyl fluoride (768-92-3) + 1,3-Difluoroadamantane (54043-61-7) + 1,3,5-trifluoroadamantane (54043-62-8) + 2-fluoroadamantane (16668-83-0)

Guidance literature:

With xenon difluoride; at 105 ℃; for 1.16667h;

DOI:10.1246/bcsj.59.1659

Reference yield:

adamantane (281-23-2) → 1-adamantyl fluoride (768-92-3) + 1,3-Difluoroadamantane (54043-61-7) + 2-fluoroadamantane (16668-83-0)

Guidance literature:

With caesium fluoroxysulphate; In methanol; acetonitrile; at 35 ℃; for 0.5h;

DOI:10.1016/S0040-4020(01)80103-4

Reference yield: 60.0%

1-styrenyloxytrimethylsilane (13735-81-4) + 1,3-Difluoroadamantane (54043-61-7) → 1,3-diphenacyladamantane (191027-11-9)

Guidance literature:

With aluminium(III) triflate; In dichloromethane; at 40 ℃; for 15h;

DOI:10.1016/j.tet.2009.02.059

upstream raw materials:

adamantane

Downstream raw materials:

adamantane

1,3-diphenacyladamantane

dinitrate of 1,3-adamantanediol