2-Benzyl-thioacrylic acid S-ethyl ester

Base Information

• Chemical Name: 2-Benzyl-thioacrylic acid S-ethyl ester
• CAS No.: 104170-03-8
• Molecular Formula: C₁₂H₁₄OS
• Molecular Weight: 206.309
• Mol file: 104170-03-8.mol

Synonyms:2-Benzyl-thioacrylic acid S-ethyl ester

Chemical Property of 2-Benzyl-thioacrylic acid S-ethyl ester

Chemical Property:

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Technology Process of 2-Benzyl-thioacrylic acid S-ethyl ester

There total 2 articles about 2-Benzyl-thioacrylic acid S-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(ethylthio)carbonyl-2-methylphenetyl bromide (104170-00-5) → 3-Ethylsulfanyl-2-methyl-2-phenyl-thiopropionic acid S-ethyl ester (104170-05-0) + 2-Methyl-3-phenyl-thiopropionic acid S-ethyl ester (104170-02-7) + 2-Benzyl-thioacrylic acid S-ethyl ester (104170-03-8)

Guidance literature:

With Ph₃Sn[Co](4-tBuPy); In benzene; Further Variations:; Reagents; Product distribution; Irradiation;

DOI:10.1002/hc.1033

Reference yield:

2-(ethylthio)carbonyl-2-methylphenetyl bromide (104170-00-5) → S-ethyl 3-phenylbutanethioate + 3-Ethylsulfanyl-2-methyl-2-phenyl-thiopropionic acid S-ethyl ester (104170-05-0) + 3-Phenyl-but-3-enethioic acid S-ethyl ester (104170-04-9) + ethyl 2-methyl-2-phenylthiopropionate (104170-01-6) + 2-Methyl-3-phenyl-thiopropionic acid S-ethyl ester (104170-02-7) + 2-Benzyl-thioacrylic acid S-ethyl ester (104170-03-8)

Guidance literature:

With Ph3Sn4-t-butylpyridine; In benzene; for 62h; Product distribution; Irradiation; other reagents, var. activation method, var. reaction time;

DOI:10.1246/cl.1995.843

Reference yield:

4-t-butylbenzenethiol (2396-68-1) + 2-Benzyl-thioacrylic acid S-ethyl ester (104170-03-8) → (S)-2-Benzyl-3-(4-tert-butyl-phenylsulfanyl)-thiopropionic acid S-ethyl ester + (R)-2-Benzyl-3-(4-tert-butyl-phenylsulfanyl)-thiopropionic acid S-ethyl ester

Guidance literature:

With (R)-SmNa₃tris(binaphthoxide); In tetrahydrofuran; dichloromethane; at -20 ℃; for 7h; Title compound not separated from byproducts;

DOI:10.1021/ja980397v

upstream raw materials:

2-(ethylthio)carbonyl-2-methylphenetyl bromide