Iodixanol

Base Information Edit

Chemical Name:Iodixanol
CAS No.:92339-11-2
Molecular Formula:C35H44I6N6O15
Molecular Weight:1550.19
Hs Code.:2924296000
European Community (EC) Number:618-837-0
NSC Number:760069
UNII:HW8W27HTXX
DSSTox Substance ID:DTXSID2045523
Nikkaji Number:J33.147C
Wikipedia:Iodixanol
Wikidata:Q2419291
NCI Thesaurus Code:C65931
RXCUI:27729
Metabolomics Workbench ID:43457
ChEMBL ID:CHEMBL1200507
Mol file:92339-11-2.mol

Synonyms:contrast media 2-5410-3;iodixanol;iodixanol-320;Visipaque;Visipaque Unique Softpac

Suppliers and Price of Iodixanol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Iodixanol
100mg
$ 1165.00

Sigma-Aldrich
Iodixanol
200mg
$ 366.00

Sigma-Aldrich
Iodixanol European Pharmacopoeia (EP) Reference Standard
$ 190.00

Sigma-Aldrich
Iodixanol European Pharmacopoeia (EP) Reference Standard
y0001294
$ 190.00

American Custom Chemicals Corporation
IODIXANOL (60% SOLUTION IN WATER) 95.00%
1G
$ 12400.00

American Custom Chemicals Corporation
IODIXANOL (60% SOLUTION IN WATER) 95.00%
10MG
$ 520.00

AHH
Iodixanol 98%
0.5g
$ 910.00

Total 158 raw suppliers

Chemical Property of Iodixanol Edit

Chemical Property:

Appearance/Colour:almost white powder
Vapor Pressure:0mmHg at 25°C
Melting Point:262-267oC (dec.)
Refractive Index:1.751
Boiling Point:1250.9 °C at 760 mmHg
PKA:11.04±0.46(Predicted)
Flash Point:710.3 °C
PSA：339.09000
Density:2.295 g/cm³
LogP:-0.02330
Storage Temp.:Refrigerator
Solubility.:Freely soluble in water, sparingly soluble in methanol, practically insoluble in methylene chloride.
XLogP3:-3.4
Hydrogen Bond Donor Count:13
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:22
Exact Mass:1549.7133
Heavy Atom Count:62
Complexity:1330

Purity/Quality:

99%, ^*data from raw suppliers

Iodixanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)N(CC(CN(C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I)C(=O)C)O)C2=C(C(=C(C(=C2I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Recent ClinicalTrials:Pediatric Risk of Hypothyroidism With Iodinated Contrast Media
Recent EU Clinical Trials:DETECTION RATE AND CLASSIFICATION OF BREAST LESIONS WITH DIGITAL MAMMOGRAPHY WITH CONTRAST MEDIUM (CEDM) ALONE AND IN COMBINATION WITH TOMOSYNTHESIS COMPARED TO MR IMAGING WITH GADOLINIUM IN DYNAMICS (DCE-MRI)
Recent NIPH Clinical Trials:None
Uses Nonionic, dimeric x-ray contrast medium. Diagnostic aid (radiopaque medium).

Technology Process of Iodixanol

There total 17 articles about Iodixanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 92339-11-2
iodixanol

Guidance literature:

Reference yield: 86.3%

: 31127-80-7
N,N'-bis(2,3-dihydroxypropyl)-5-acetamido-2,4,6-triiodoisophthalamide

: 106-89-8,24969-06-0,13403-37-7
epichlorohydrin

: 66108-95-0
iohexol

: 92339-11-2
iodixanol

Guidance literature:: With hydrogenchloride; boric acid; potassium hydroxide; In water; pH=10 - 11; Product distribution / selectivity; Industry scale;