ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate

Base Information

Chemical Name:ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate
CAS No.:287379-47-9
Molecular Formula:C₂₃H₂₁BrN₂O₅S
Molecular Weight:517.4
Hs Code.:

Synonyms:ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate

Suppliers and Price of ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate

There total 4 articles about ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 287379-32-2
4-But-2-ynyloxy-N-methyl-benzenesulfonamide

: 206258-97-1
ethyl 4-chloro-8-bromo-3-quinolinecarboxylate

: 287379-47-9
ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00127-6

Reference yield:

: 35975-57-6
ethyl-8-bromo-4-hydroxyquinolyl-3-carboxylic acid ethyl ester

: 287379-47-9
ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃

2: NaH / dimethylformamide

With sodium hydride; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00127-6

Reference yield:

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 287379-47-9
ethyl 8-bromo-4-[{[4-(2-butynyloxy)phenyl]sulfonyl}(methyl)amino]-3-quinolinecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 120 - 150 °C

1.2: Heating

2.1: POCl₃

3.1: NaH / dimethylformamide

With sodium hydride; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00127-6