N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate

Base Information

Chemical Name:N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate
CAS No.:1378110-08-7
Molecular Formula:C₂HF₃O₂*C₁₆H₁₉N₃O₃S
Molecular Weight:447.435
Hs Code.:

Synonyms:N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate

Suppliers and Price of N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate

Chemical Property:

Purity/Quality:: 99% ，98% ^*data from raw suppliers

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Technology Process of N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate

There total 5 articles about N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1378110-13-4
N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate

: 76-05-1
trifluoroacetic acid

: 1378110-08-7
N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate

Guidance literature:: In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 88-75-5,78813-12-4
2-hydroxynitrobenzene

: 1378110-08-7
N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1: triphenylphosphine; diethylazodicarboxylate / 2 h / 20 °C

2: hydrogen / palladium on activated charcoal / methanol / 2 h / 20 °C / 3750.38 Torr

3: pyridine / dichloromethane / 3 h / 20 °C

4: dichloromethane / 2 h / 20 °C

With pyridine; hydrogen; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In methanol; dichloromethane; 1: Mitsunobu reaction;

Reference yield:

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: 1378110-08-7
N-(2-(piperidin-4-yloxy)phenyl)pyridine-2-sulfonamide trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1: triphenylphosphine; diethylazodicarboxylate / 2 h / 20 °C

2: hydrogen / palladium on activated charcoal / methanol / 2 h / 20 °C / 3750.38 Torr

3: pyridine / dichloromethane / 3 h / 20 °C

4: dichloromethane / 2 h / 20 °C

With pyridine; hydrogen; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In methanol; dichloromethane; 1: Mitsunobu reaction;