(7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)(2-chlorophenyl)methanone

Base Information

Chemical Name:(7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)(2-chlorophenyl)methanone
CAS No.:164526-16-3
Molecular Formula:C₁₅H₁₂ClNO₃
Molecular Weight:289.718
Hs Code.:
DSSTox Substance ID:DTXSID201161237
Mol file:164526-16-3.mol

Synonyms:164526-16-3;(7-amino-2,3-dihydro-1,4-benzodioxin-6-yl)(2-chlorophenyl)methanone;(7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(2-chlorophenyl)methanone;(6-amino-2,3-dihydro-1,4-benzodioxin-7-yl)-(2-chlorophenyl)methanone;(7-amino-2,3-dihydro-benzo[1,4]dioxin-6-yl)-(2-chloro-phenyl)-methanone;MFCD00561832;Oprea1_052538;Oprea1_586027;DTXSID201161237;STK098019;AKOS001611871;CS-0318457;2-amino-4,5-ethylenedioxy-2'-chlorobenzophenone;(7-Amino-2,3-dihydrobenzo[1,4]dioxin-6-yl) (2-chlorophenyl)methanone

Suppliers and Price of (7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)(2-chlorophenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(2-chlorophenyl)methanone 97%
1g
$ 583.00

American Custom Chemicals Corporation
(7-AMINO-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)(2-CHLOROPHENYL)METHANONE 95.00%
5MG
$ 501.17

Total 2 raw suppliers

Chemical Property of (7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)(2-chlorophenyl)methanone

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:289.0505709
Heavy Atom Count:20
Complexity:365

Purity/Quality:

99% ^*data from raw suppliers

(7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(2-chlorophenyl)methanone 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COC2=C(O1)C=C(C(=C2)N)C(=O)C3=CC=CC=C3Cl

Technology Process of (7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)(2-chlorophenyl)methanone

There total 3 articles about (7-Amino-2,3-dihydro-1,4-benzodioxin-6-yl)(2-chlorophenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 936078-04-5
C₁₈H₁₄ClNO₄

: 141-52-6
sodium ethanolate

: 1354395-87-1
N-[7-(2-chlorobenzoyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-3-ethoxypropionamide

: 164526-16-3
7-amino-2,3-dihydro-1,4-benzodioxin-6-yl 2-chlorophenyl ketone

Guidance literature:: In ethanol; at 78 ℃; for 2h;
DOI:10.1007/s10593-011-0881-2

Reference yield: 71.0%

: 164526-11-8
6-(2-chlorobenzoyl)-7-nitro-1,4-benzodioxane

: 164526-16-3
7-amino-2,3-dihydro-1,4-benzodioxin-6-yl 2-chlorophenyl ketone

Guidance literature:: With hydrogenchloride; iron; In ethanol; at 78 ℃; for 6h;
DOI:10.1007/BF01169826

Reference yield:

: 164526-07-2
6-(2-chlorobenzoyl)-1,4-benzodioxane

: 164526-16-3
7-amino-2,3-dihydro-1,4-benzodioxin-6-yl 2-chlorophenyl ketone

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / HNO₃, H₂SO₄ / acetic acid / 1 h / 10 - 20 °C

2: 71 percent / Fe, HCl / ethanol / 6 h / 78 °C

With hydrogenchloride; sulfuric acid; nitric acid; iron; In ethanol; acetic acid;
DOI:10.1007/BF01169826