Z-Leu-OMpt

Base Information

• Chemical Name: Z-Leu-OMpt
• CAS No.: 120979-53-5
• Molecular Formula: C₁₆H₂₄NO₄PS
• Molecular Weight: 357.411
• Mol file: 120979-53-5.mol

Synonyms:Z-Leu-OMpt

Chemical Property of Z-Leu-OMpt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Z-Leu-OMpt

There total 1 articles about Z-Leu-OMpt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Z-Leu-OH (2018-66-8) + dimethylphosphinothioic chloride (993-12-4) → Z-Leu-OMpt (120979-53-5)

Guidance literature:

With triethylamine; In chloroform; for 0.333333h; Ambient temperature;

DOI:10.1246/bcsj.61.3653

Reference yield: 98.0%

L-asparagine amide (16748-73-5) + Z-Leu-OMpt (120979-53-5) → (N-Cbz-leucyl)asparagyl-NH2 (39802-47-6)

Guidance literature:

With triethylamine; In methanol; water; 20 min; 24 h, 0 deg C;

DOI:10.1246/bcsj.61.3653

Reference yield: 80.0%

Z-Leu-OMpt (120979-53-5) + H-Asn-Ser-Ile-Leu-Asn-NH2 (45314-98-5) → Z-Leu-Asn-Ser-Ile-Leu-Asn-NH2 (39802-58-9)

Guidance literature:

With triethylamine; In methanol; water; 0 deg C, 20 min; 48 h, 0 deg C;

DOI:10.1246/bcsj.61.3653

upstream raw materials:

Z-Leu-OH

dimethylphosphinothioic chloride

Downstream raw materials:

(N-Cbz-leucyl)asparagyl-NH₂

Z-Leu-Asn-Ser-Ile-Leu-Asn-NH₂

Z-Ile-Leu-Asn-NH₂

Z-Ser-Ile-Leu-Asn-NH₂